Tămaş S I, Roman L
Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Med Interna. 1989 Mar-Apr;41(2):143-7.
The paper studies the effect of a blocking agent, calcium-niphedipine (corinfar), single or associated with other hypertensors (diuretic, sympathico-colitic), in a dose of 30 mm (3 X 10 mg) administered for about 8-10 days on a lot of 90 patients, men and women, with essentially noncomplicated AHT or associated with: pyelonephritis, cardiac insufficiency, ischemic cerebral stroke, rhythm and conduction disturbances. The systolic AT values of the patients ranged between 160 and 300 mmHg and the diastolic AT between 90 and 150 mmHg. The systolic AT decreased significantly with 40-117 mmHg and the diastolic AT with 15-55 mmHg. The drug was well tolerated and no side effect was noticed. In two cases, the AT values were not influenced by the treatment.
该论文研究了一种阻滞剂硝苯地平钙（可立平）单独使用或与其他降压药（利尿剂、交感神经阻滞剂）联合使用的效果，以30毫克（3×10毫克）的剂量对90名男女患者给药约8至10天，这些患者患有基本无并发症的高血压或合并有：肾盂肾炎、心脏功能不全、缺血性脑卒、心律和传导紊乱。患者的收缩压范围在160至300毫米汞柱之间，舒张压在90至150毫米汞柱之间。收缩压显著下降了40至117毫米汞柱，舒张压下降了15至55毫米汞柱。该药物耐受性良好，未观察到副作用。有两例患者的血压值不受治疗影响。
