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硝苯地平治疗动脉高血压

[Nifedipine in the treatment of arterial hypertension].

作者信息

Monova D, Dzhoneva S, Simeonova N, Dimitrova V, Stoianova M

出版信息

Vutr Boles. 1987;26(1):57-60.

PMID:3590730
Abstract

The results are reported from the administration of nifedipine to 39 patients with arterial hypertension. Thirty one of the patients suffered from hypertonic disease, and 8 had symptomatic hypertension. Light hypertension was established in 26 of the patients, moderate--10 and grave--3. In 22 of the patients (66.6%)--16 with light and 6 with moderate hypertension, the arterial pressure was normalized by the administration of nifedipine alone, 40 mg daily. In 16 patients the arterial hypertension was coped with the addition of beta-blockers, diuretic and clonidine. Only one patient failed to respond to the treatment. The effect advanced on 3rd--4th day on the average with the treatment with nifedipine alone and after 4-6 days after the inclusion of the double combination. Negligible and transitory adverse effects were observed in single patients. Nifedipine, administered alone or in combination with beta-blockers, diuretic and clonidine is an excellent agent in the treatment of light and moderate arterial hypertension.

摘要

报告了对39例动脉高血压患者使用硝苯地平的结果。其中31例患有高血压病,8例有症状性高血压。26例患者为轻度高血压,10例为中度,3例为重度。22例患者(66.6%)——16例轻度高血压和6例中度高血压患者,仅通过每日服用40毫克硝苯地平,动脉血压就恢复了正常。16例患者通过加用β受体阻滞剂、利尿剂和可乐定控制了动脉高血压。只有1例患者对治疗无反应。单独使用硝苯地平时,平均在第3至4天起效,加入联合用药后4至6天起效。个别患者出现轻微且短暂的不良反应。单独使用或与β受体阻滞剂、利尿剂和可乐定联合使用时,硝苯地平是治疗轻度和中度动脉高血压的优秀药物。

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