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[A case of pancreatic cancer with distant metastasis successfully resected after neoadjuvant chemotherapy with a combination of S-1 and gemcitabine].

作者信息

Maeda Tetsuya, Tsuchiya Masaru, Ishii Jun, Koda Takamaru, Kubota Yoshihisa, Katagiri Toshio, Tamura Akira, Otsuka Yuichiro, Shibuya Kazutoshi, Kaneko Hironori

机构信息

Dept. of Surgery Toho University School of Medicine.

出版信息

Gan To Kagaku Ryoho. 2014 Nov;41(12):2184-6.

Abstract

The patient was a 70-year-old man with a chief complaint of cough.After careful examination, he was diagnosed with pancreatic body cancer with metastasis to the liver and right pleura and with early gastric cancer.He was treated with S-1 and gemcitabine combination chemotherapy.After completing 3 courses, the distant metastasis could no longer be observed. After completing 4 courses, the tumor marker level in the serum was normalized.The pancreatic lesion was restricted by the end of 10 courses, and the pancreas body and tail were resected.After additional chemotherapy with S-1, he was switched to weekly paclitaxel therapy because of peritoneal dissemination.The patient survived for 15 months after surgery.In cases of unresectable pancreatic cancer with distant metastasis, it may be possible to consider the surgical option when chemotherapy is effective.

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