Maeda Tetsuya, Tsuchiya Masaru, Ishii Jun, Koda Takamaru, Kubota Yoshihisa, Katagiri Toshio, Tamura Akira, Otsuka Yuichiro, Shibuya Kazutoshi, Kaneko Hironori
Dept. of Surgery Toho University School of Medicine.
Gan To Kagaku Ryoho. 2014 Nov;41(12):2184-6.
The patient was a 70-year-old man with a chief complaint of cough.After careful examination, he was diagnosed with pancreatic body cancer with metastasis to the liver and right pleura and with early gastric cancer.He was treated with S-1 and gemcitabine combination chemotherapy.After completing 3 courses, the distant metastasis could no longer be observed. After completing 4 courses, the tumor marker level in the serum was normalized.The pancreatic lesion was restricted by the end of 10 courses, and the pancreas body and tail were resected.After additional chemotherapy with S-1, he was switched to weekly paclitaxel therapy because of peritoneal dissemination.The patient survived for 15 months after surgery.In cases of unresectable pancreatic cancer with distant metastasis, it may be possible to consider the surgical option when chemotherapy is effective.
该患者为一名70岁男性，主诉咳嗽。经过仔细检查，他被诊断为胰体癌伴肝和右胸膜转移以及早期胃癌。他接受了S-1和吉西他滨联合化疗。完成3个疗程后，已无法观察到远处转移。完成4个疗程后，血清中的肿瘤标志物水平恢复正常。在10个疗程结束时，胰腺病变得到局限，遂切除胰体和胰尾。在接受S-1辅助化疗后，由于腹膜播散，他改为每周一次的紫杉醇治疗。该患者术后存活了15个月。对于伴有远处转移的不可切除胰腺癌病例，当化疗有效时，或许可以考虑手术选择。
