Okada Kazuyuki, Ebisui Chikara, Nushijima Yoichiro, Yanagisawa Tetsu, Okamura Shu, Fukuchi Nariaki, Murata Kohei, Yokouchi Hideoki, Kinuta Masakatsu
Dept. of Surgery, Suita Municipal Hospital.
Gan To Kagaku Ryoho. 2014 Nov;41(12):2361-3.
A 66-year-old man underwent a curative operation for advanced gastric cancer (T4aN0M0, Stage IIB). A gastric cancer recurrence with paraaortic lymph node (PALN) metastasis was diagnosed fifteen months after the operation. Systemic chemotherapy was initiated, using a regimen of S-1/CDDP. After 7 courses, abdominal computed tomography (CT) examination indicated the regression of PALN swelling. However, peritoneal dissemination was detected in the neighborhood of the right kidney. S-1/docetaxel (S-1/DOC) was selected as the second-line chemotherapy. After 3 courses, the peritoneal dissemination could not be detected. Five years since the curative operation, the patient has been doing well, with no signs of recurrence. In summary, we successfully treated a case of peritoneal dissemination from gastric cancer with S-1/DOC chemo- therapy.
一名66岁男性接受了晚期胃癌（T4aN0M0，IIB期）的根治性手术。术后15个月诊断为胃癌复发并伴有主动脉旁淋巴结（PALN）转移。开始使用S-1/顺铂方案进行全身化疗。7个疗程后，腹部计算机断层扫描（CT）检查显示PALN肿大消退。然而，在右肾附近发现了腹膜播散。选择S-1/多西他赛（S-1/DOC）作为二线化疗方案。3个疗程后，未检测到腹膜播散。根治性手术后5年，患者情况良好，无复发迹象。总之，我们用S-1/DOC化疗成功治疗了一例胃癌腹膜播散病例。
