Hiraki Sakurao, Kuwahara Taichi, Harada Toshio, Kawaoka Toru, Fukuda Shintaro, Imoto Shinobu
Dept. of Surgery, Ube Industries, Ltd. Central Hospital.
Gan To Kagaku Ryoho. 2014 Nov;41(12):2456-8.
We report a case of multiple intestinal lymphomas accompanied by rapid growth of cutaneous infiltration after surgery. An 86-year-old woman visited our hospital complaining of lower abdominal pain. Multiple tumors in the sigmoidal and ascending colon were detected by using colonoscopy and computed tomography; therefore, we performed surgery. Postoperative pathological examination identified the sigmoidal colon tumor as an adenocarcinoma and the ascending colon tumor as a B cell lymphoma. The tumors in the ileum and the ileal diverticulum, which were simultaneously excised, were also diagnosed as B-cell lymphomas. After surgery, rapid appearance of multiple light purple nodules on the skin of the right thigh was observed. Histological examination of biopsied skin nodules led to a diagnosis of B-cell lymphoma, similar to the previously removed tumors. Although radiotherapy and chemotherapy were administered to the dermatological lesion that reached an advanced stage, the disease condition was progressive. The patient was transferred to another hospital to receive medical treatment 3 months postoperatively. We consider these dermatological lesions to be dermal infiltration of B-cell lymphomas originating from tumors in the intestinal tract.
我们报告一例多发性肠道淋巴瘤患者,术后皮肤浸润迅速生长。一名86岁女性因下腹部疼痛前来我院就诊。通过结肠镜检查和计算机断层扫描发现乙状结肠和升结肠有多个肿瘤;因此,我们进行了手术。术后病理检查确定乙状结肠肿瘤为腺癌,升结肠肿瘤为B细胞淋巴瘤。同时切除的回肠和回肠憩室中的肿瘤也被诊断为B细胞淋巴瘤。术后,观察到右大腿皮肤迅速出现多个浅紫色结节。对活检的皮肤结节进行组织学检查,诊断为B细胞淋巴瘤,与先前切除的肿瘤相似。尽管对已发展到晚期的皮肤病变进行了放疗和化疗,但病情仍在进展。患者术后3个月转至另一家医院接受治疗。我们认为这些皮肤病变是源于肠道肿瘤的B细胞淋巴瘤的皮肤浸润。