Osawa Hideki, Nishimura Junichi, Inoue Akira, Ueda Masami, Mokutani Yukako, Miyo Masaaki, Naito Atsushi, Hamabe Atsushi, Hiraki Masayuki, Matsumura Tae, Munakata Koji, Ogino Takayuki, Takahashi Yusuke, Uemura Mamoru, Hata Taishi, Takemasa Ichiro, Mizushima Tsunekazu, Yamamoto Hirofumi, Doki Yuichiro, Mori Masaki
Dept. of Gastroenterological Surgery, Graduate School of Medicine, Osaka University.
Gan To Kagaku Ryoho. 2014 Nov;41(12):2493-5.
Solitary fibrous tumor (SFT) are relatively rare neoplasms that usually arise in the thoracic cavity in adults. Although many cases of extrathoracic SFT have been recently reported, SFT from the omentum is rare. A 32-year-old woman consulted a gynecologist complaining of irregular vaginal bleeding. Magnetic resonance imaging (MRI) revealed a tumor in the omentum, and the patient was admitted to our department. The patient underwent laparoscopic tumorectomy. The tumor size was 48 × 35 × 30 mm, and grayish-white nodules were observed. Histological examination showed hyperplastic spindle-shaped tumor cells with a pattern-less arrangement. Immunohistochemical staining showed the tumor was positive for CD34 and bcl-2, slightly positive for alpha smooth muscle actin(a-SMA), and negative for S-100 and c-kit. Accordingly, a diagnosis of SFT was made. The patient has not shown any recurrence 12 months after surgery. Most SFTs are benign, although there are some reports of recurring tumors. There are no clear guidelines for the treatment of SFT because of its rarity. Therefore, close long-term follow-up should be performed.
孤立性纤维瘤(SFT)是相对罕见的肿瘤,通常发生于成人的胸腔。尽管最近有许多胸外SFT病例的报道,但来自大网膜的SFT却很罕见。一名32岁女性因不规则阴道出血咨询妇科医生。磁共振成像(MRI)显示大网膜有一个肿瘤,该患者被收入我科。患者接受了腹腔镜肿瘤切除术。肿瘤大小为48×35×30mm,可见灰白色结节。组织学检查显示增生的梭形肿瘤细胞排列无规律。免疫组化染色显示肿瘤CD34和bcl-2阳性,α平滑肌肌动蛋白(α-SMA)弱阳性,S-100和c-kit阴性。因此,诊断为SFT。该患者术后12个月未出现任何复发。大多数SFT是良性的,尽管有一些复发性肿瘤的报道。由于SFT罕见,目前尚无明确的治疗指南。因此,应进行密切的长期随访。