Ku Yixuan, Bodner Mark, Zhou Yong-Di
Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University, Shanghai, 200062, China,
Neurosci Bull. 2015 Apr;31(2):175-82. doi: 10.1007/s12264-014-1503-7. Epub 2015 Mar 2.
The activity in sensory cortices and the prefrontal cortex (PFC) throughout the delay interval of working memory (WM) tasks reflect two aspects of WM-quality and quantity, respectively. The delay activity in sensory cortices is fine-tuned to sensory information and forms the neural basis of the precision of WM storage, while the delay activity in the PFC appears to represent behavioral goals and filters out irrelevant distractions, forming the neural basis of the quantity of task-relevant information in WM. The PFC and sensory cortices interact through different frequency bands of neuronal oscillation (theta, alpha, and gamma) to fulfill goal-directed behaviors.
在工作记忆(WM)任务的整个延迟间隔期间,感觉皮层和前额叶皮层(PFC)的活动分别反映了WM的两个方面——质量和数量。感觉皮层中的延迟活动会根据感觉信息进行微调,形成WM存储精度的神经基础,而PFC中的延迟活动似乎代表行为目标并过滤掉无关的干扰,形成WM中与任务相关信息数量的神经基础。PFC和感觉皮层通过神经元振荡的不同频段(theta、alpha和gamma)相互作用,以实现目标导向行为。