Misra Satya Ranjan, Saigal Anjali, Rastogi Varun, Priyadarshini Smita R, Pati Abhishek Ranjan
Reader, Department of Oral Medicine & Radiology, Institute of Dental Sciences , Bhubaneswar, Odisha, India .
Reader, Department of Oral Medicine & Radiology, Dasmesh Institute of Research & Dental Sciences , Talwandi Road, Faridkot, Punjab, India .
J Clin Diagn Res. 2015 Jan;9(1):ZD08-11. doi: 10.7860/JCDR/2015/11192.5417. Epub 2015 Jan 1.
Central ossifying fibroma (COF) is a rare benign fibro-osseous neoplasm which has a predilection for mandible and is encountered in middle aged women. It arises from mesenchymal blast cells of the periodontal ligament, and with a potential to form fibrous tissue, cementum and bone. It is a well circumscribed lesion mainly comprising of fibrous tissue with varying amounts of bone or cementum or osteo-cementum like tissue. We present an uncommon case of COF of the maxilla in a 35-year-old male who presented with a pus discharging sinus in the maxilla. Due to the bizarre size of the lesion we have termed as 'giant' COF. There is extensive facial asymmetry on the right side with obliteration of the maxillary antrum, deviation of the nose and upward displacement of the orbit.
中央型骨化性纤维瘤（COF）是一种罕见的良性纤维-骨肿瘤，好发于下颌骨，多见于中年女性。它起源于牙周膜的间充质母细胞，有形成纤维组织、牙骨质和骨的潜能。它是一种边界清楚的病变，主要由纤维组织组成，伴有不同数量的骨、牙骨质或类骨牙骨质组织。我们报告一例35岁男性上颌骨COF的罕见病例，该患者上颌骨有一个排脓窦道。由于病变尺寸异常巨大，我们将其称为“巨大型”COF。右侧面部存在广泛不对称，上颌窦消失，鼻偏斜，眼眶向上移位。
