Department of Oral Diagnosis, Medicine and Radiology, MGV's K.B.H. Dental College and Hospital, Nashik, Maharashtra, India.
Oral Oncol. 2011 Sep;47(9):804-9. doi: 10.1016/j.oraloncology.2011.06.014. Epub 2011 Jul 8.
Ossifying fibromas are uncommon benign tumors of the craniofacial skeleton thought to originate from the periodontal ligament. Most are small and incidentally diagnosed with routine dental radiographs. With larger lesions, patients may complain of an abnormal bite or an enlarging mass. This tumor involves slow-evolving growth with deforming swelling generally arising in the mandible, with possible early tooth displacement. From the radiological perspective, more than 50% of the lesions exhibit an expansion of the jaws and 53% shows well-defined unilocular radiolucencies and 40% are mixed radiolucent-radiopaque lesions. The lesions exceptionally can be radiopaque. Ossifying fibroma presents several variant histopathological subtypes. The overlapping clinical and histopathological features of these subtypes have led to diagnostic dilemma and confusion. Complete excision of this tumor has become a necessity since it is notorious for recurrence. We present here two cases of ossifying fibroma of the jaws along with insight into the literature review.
骨化性纤维瘤是一种罕见的颅面骨良性肿瘤，被认为起源于牙周韧带。大多数肿瘤较小，在常规牙科 X 光片检查中偶然发现。对于较大的病变，患者可能会抱怨咬合异常或肿块增大。这种肿瘤生长缓慢，通常在颌骨中出现变形肿胀，可能导致早期牙齿移位。从影像学角度来看，超过 50%的病变表现为颌骨扩张，53%显示清晰的单房性透亮区，40%为混合性透亮-不透光病变。这种病变偶尔也可能是不透光的。骨化性纤维瘤有几种变异的组织病理学亚型。这些亚型的重叠临床表现和组织病理学特征导致了诊断上的困境和混淆。由于该肿瘤极易复发，因此彻底切除已成为必要。我们在此介绍两例颌骨骨化性纤维瘤病例，并结合文献复习进行分析。
