The closely related rare and severe acute myeloid leukemias carrying EVI1 or PRDM16 rearrangements share singular biological features.
作者信息
Eveillard Marion, Delaunay Jacques, Richebourg Steven, Lodé Laurence, Garand Richard, Wuillème Soraya, Duhoux François, Antoine-Poirel Hélène, Godon Catherine, Béné Marie C
机构信息
Hematology Laboratory, University Hospital, Nantes, France
Hematology Clinic, University Hospital, Nantes, France.
出版信息
Haematologica. 2015 Mar;100(3):e114-5. doi: 10.3324/haematol.2014.121079.
Abstract
摘要
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The closely related rare and severe acute myeloid leukemias carrying EVI1 or PRDM16 rearrangements share singular biological features.携带EVI1或PRDM16重排的密切相关的罕见且严重的急性髓系白血病具有独特的生物学特征。
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2
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Haematologica. 2014 Nov;99(11):e225-7. doi: 10.3324/haematol.2014.107128. Epub 2014 Jul 11.
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A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression.远程 GATA2 造血增强子通过激活 EVI1 表达驱动 inv(3)(q21;q26) 白血病的发生。
Cancer Cell. 2014 Apr 14;25(4):415-27. doi: 10.1016/j.ccr.2014.02.008. Epub 2014 Apr 3.
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