Klooster Karin, ten Hacken Nick H T, Hartman Jorine E, Kerstjens Huib A M, Slebos Dirk-Jan
Universitair Medisch Centrum Groningen, afd. Longziekten en Tuberculose, Groningen.
Ned Tijdschr Geneeskd. 2015;159:A8497.
The current drug treatment of patients with severe and very severe COPD is often insufficient to achieve an acceptable quality of life. Surgical treatment of patients with COPD, by means of lung volume reduction surgery or lung transplantation is invasive and only available to a limited number of patients. Bronchoscopic lung volume reduction is a novel, minimally invasive, experimental treatment option for patients with severe COPD. Two different treatment options are currently available, depending on the type of pulmonary emphysema: bronchoscopic intervention with one-way endobronchial valves or with lung volume reduction coils. In selected patients with severe emphysema, bronchoscopic lung volume reduction brings about a clinically relevant improvement in pulmonary function, exercise capacity and quality of life. In view of the innovative and specialist nature of bronchoscopic lung volume reduction, it is prudent to perform this treatment in a centre of expertise for COPD.
目前，对于重度和极重度慢性阻塞性肺疾病（COPD）患者的药物治疗往往不足以实现可接受的生活质量。COPD患者的手术治疗，如肺减容手术或肺移植，具有侵入性，且仅适用于少数患者。支气管镜下肺减容术是一种针对重度COPD患者的新型、微创的实验性治疗选择。根据肺气肿的类型，目前有两种不同的治疗选择：使用单向支气管内瓣膜或肺减容线圈进行支气管镜干预。在选定的重度肺气肿患者中，支气管镜下肺减容术可在临床相关方面改善肺功能、运动能力和生活质量。鉴于支气管镜下肺减容术的创新性和专业性，在COPD专业治疗中心进行这种治疗是谨慎的做法。
