Çift Hakan, Özkan Feyza Ünlü, Tolu Sena, Şeker Ali, Mahiroğulları Mahir
Department of Orthopedics and Traumatology, İstanbul Medipol University, 34214 Bağcılar, İstanbul, Turkey.
Eklem Hastalik Cerrahisi. 2015;26(1):16-20. doi: 10.5606/ehc.2015.05.
This study aims to assess and compare the efficacy of subacromial tenoxicam and steroid injections in treating patients with shoulder impingement syndrome.
Forty patients having shoulder impingement syndrome with findings of rotator cuff tendinitis or subacromial bursitis on magnetic resonance imaging were included in the study. Patients were randomized into two subacromial injection groups: patients in the first group (10 males, 10 females; mean age 45.3 years; range 32 to 67 years) were administered 20 mg tenoxicam three times by weekly intervals, and patients in the second group (8 males, 12 females; mean age 46.5 years; range 29 to 73 years) were administered 40 mg methylprednisolone acetate just for once. Visual analog scale (VAS), active range of motion (ROM) of the shoulder joint, and Disabilities of Arm, Shoulder and Hand (DASH) questionnaire scores were evaluated at baseline, six weeks after treatment, and first year.
Visual analog scale, DASH, and active ROM scores in both groups were statistically significantly improved. No statistically significant difference was detected between subacromial tenoxicam and steroid injections in terms of post-treatment VAS, DASH, and active ROM scores. Mean pre- and post-treatment VAS scores in tenoxicam group were 7.8 (range, 3-9) and 2.6 (range, 2-4), respectively. Mean pre- and post-treatment VAS scores in steroid group were 6.2 (range, 3-10) and 3.6 (range, 0-7), respectively. Mean pre- and post-treatment DASH scores in tenoxicam group were 59.4 (range, 45-80) and 14.7 (range, 8.3-25.8), respectively. Mean pre- and post-treatment DASH scores in steroid group were 56.7 (range, 33.3-85.8) and 18.1 (range, 0-69.2), respectively. Although the improvement in active ROM was higher in the steroid group, difference between two groups was not statistically significant.
Both subacromial tenoxicam and steroid injections may be successfully used in the treatment of patients with impingement syndrome. Subacromial tenoxicam injection may be preferred as a first-line intervention in these patients thanks to its safe profile.
本研究旨在评估和比较肩峰下注射替诺昔康和类固醇治疗肩峰撞击综合征患者的疗效。
本研究纳入40例经磁共振成像检查发现有肩袖肌腱炎或肩峰下滑囊炎的肩峰撞击综合征患者。患者被随机分为两个肩峰下注射组:第一组(10例男性,10例女性;平均年龄45.3岁;范围32至67岁)患者每隔一周接受3次20mg替诺昔康注射,第二组(8例男性,12例女性;平均年龄46.5岁;范围29至73岁)患者仅接受1次40mg醋酸甲泼尼龙注射。在基线、治疗后6周和第1年评估视觉模拟量表(VAS)、肩关节活动范围(ROM)以及上肢、肩部和手部功能障碍(DASH)问卷评分。
两组的视觉模拟量表、DASH和主动ROM评分在统计学上均有显著改善。肩峰下注射替诺昔康和类固醇在治疗后VAS、DASH和主动ROM评分方面未检测到统计学显著差异。替诺昔康组治疗前和治疗后的平均VAS评分分别为7.8(范围3 - 9)和2.6(范围2 - 4)。类固醇组治疗前和治疗后的平均VAS评分分别为6.2(范围3 - 10)和3.6(范围0 - 7)。替诺昔康组治疗前和治疗后的平均DASH评分分别为59.4(范围45 - 80)和14.7(范围8.3 - 25.8)。类固醇组治疗前和治疗后的平均DASH评分分别为56.7(范围33.3 - 85.8)和18.1(范围0 - 69.2)。尽管类固醇组主动ROM的改善更高,但两组之间的差异无统计学意义。
肩峰下注射替诺昔康和类固醇均可成功用于治疗撞击综合征患者。由于其安全性,肩峰下注射替诺昔康可能是这些患者的一线首选干预措施。