Smith J A, Hutson J M, Beasley S W, Reddihough D S
Department of General Paediatrics, Royal Children's Hospital, Melbourne, Australia.
J Pediatr Surg. 1989 Dec;24(12):1303-5. doi: 10.1016/s0022-3468(89)80572-x.
This study examined the reported association between cerebral palsy and cryptorchidism. A comparison was made among 25 boys with cerebral palsy under the age of 2 years and 6 months, 25 boys with cerebral palsy aged between 5 and 10 years, and age-matched controls. The testes remained in the same position with age in boys with cerebral palsy, whereas in normal children the testes were slightly lower initially (P less than .005) and became lower still with growth (P less than .001). This result, taken in conjunction with previous studies, casts doubts on the theories of early damage to the hypothalamic-pituitary-gonadal axis as the cause of maldescent in cerebral palsy. It is postulated that any apparent increase in cryptorchidism in older patients with cerebral palsy may be caused by spasticity of the cremaster muscle leading to pathologic retraction of the testis out of the scrotum.
本研究调查了所报道的脑瘫与隐睾症之间的关联。对25名年龄在2岁6个月以下的脑瘫男童、25名年龄在5至10岁的脑瘫男童以及年龄匹配的对照组进行了比较。脑瘫男童的睾丸位置随年龄保持不变,而正常儿童的睾丸最初位置略低(P<0.005),并随着生长进一步下降(P<0.001)。结合先前的研究,这一结果对下丘脑-垂体-性腺轴早期受损是脑瘫患儿睾丸下降不全原因的理论提出了质疑。据推测,大龄脑瘫患者中隐睾症的任何明显增加可能是由提睾肌痉挛导致睾丸病理性回缩至阴囊外所致。