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隐睾症的手术治疗:指南与现实——对3587例病例的10年观察分析

Operative management of cryptorchidism: guidelines and reality--a 10-year observational analysis of 3587 cases.

作者信息

Hensel Kai O, Caspers Tawa, Jenke Andreas C, Schuler Ekkehard, Wirth Stefan

机构信息

Department of Pediatrics, HELIOS Medical Center Wuppertal, Children's Hospital, Centre for Clinical & Translational Research (CCTR), Faculty of Health, Witten/Herdecke University, Heusnerstr. 40, D-42283, Wuppertal, Germany.

Institute for Quality Management, HELIOS Kliniken GmbH, Berlin, Germany.

出版信息

BMC Pediatr. 2015 Sep 10;15:116. doi: 10.1186/s12887-015-0429-1.

Abstract

BACKGROUND

Undescended testis (UDT) is the most common disorder in pediatric surgery and one of the most important risk factors for malignancy and subfertility. In 2009 local guidelines were modified and now recommend treatment to be completed by the age of 1. Aim of this study was to analyze age distribution at the time of orchidopexy, whether the procedure is performed according to guideline recommendations and to assess primary care pediatricians' attitude regarding their treatment approach.

METHODS

We retrospectively analyzed 3587 patients with UDT regarding age at orchidopexy between 2003 and 2012 in 13 German hospitals. Furthermore, we conducted an anonymized nation-wide survey among primary care pediatricians regarding their attitude toward management of UDT.

RESULTS

Before modification of the guideline 78% (n = 1245) of the boys with UDT were not operated according to guideline recommendations. After the modification that number rose to 95% (n = 1472). 42% of the orchidopexies were performed on patients aged 4 to 17 years. 46% of the primary care pediatricians were not aware of this discrepancy and 38% would only initiate operative management after the first year of life. In hospitals with pediatric surgery departments significantly more patients received orchidopexy in their first year of life (p < .001).

CONCLUSION

The guideline for UDT in Germany has not yet been implemented sufficiently. Timing of orchidopexy must be optimized in order to improve long-term prognosis. Both primary care providers and parents should be educated regarding the advantages of early orchidopexy in UDT. Prospective studies are needed to elucidate the high rate of late orchidopexies.

摘要

背景

隐睾是小儿外科最常见的疾病,也是发生恶性肿瘤和生育力低下的最重要危险因素之一。2009年,当地指南进行了修订,现在建议在1岁前完成治疗。本研究的目的是分析睾丸固定术时的年龄分布情况,该手术是否按照指南建议进行,并评估基层儿科医生对其治疗方法的态度。

方法

我们回顾性分析了2003年至2012年期间德国13家医院的3587例隐睾患者的睾丸固定术年龄。此外,我们对基层儿科医生就其对隐睾管理的态度进行了全国范围的匿名调查。

结果

在指南修订之前,78%(n = 1245)的隐睾男孩未按照指南建议进行手术。修订后,这一数字上升到95%(n = 1472)。42%的睾丸固定术是在4至17岁的患者中进行的。46%的基层儿科医生没有意识到这种差异,38%的医生只会在患儿1岁以后才开始进行手术治疗。在设有小儿外科的医院中,明显有更多患者在1岁以内接受了睾丸固定术(p < 0.001)。

结论

德国隐睾指南尚未得到充分实施。必须优化睾丸固定术的时机,以改善长期预后。应向基层医疗服务提供者和家长宣传早期睾丸固定术治疗隐睾的优势。需要进行前瞻性研究以阐明晚期睾丸固定术比例较高的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bc9/4566496/a615d7391158/12887_2015_429_Fig1_HTML.jpg

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