Alonso Roberto, Aguilera Antonio, Córdoba Juan, Fuertes Antonio
Servicio de Microbiología y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, España.
Servicio de Microbiología, Complexo Hospitalario Universitario de Santiago, Santiago de Compostela, España.
Enferm Infecc Microbiol Clin. 2015 Nov;33(9):e53-62. doi: 10.1016/j.eimc.2014.08.002. Epub 2015 Mar 3.
Liver inflammation or hepatitis has many different causes, both infectious and non-infectious. Among the former, viral infection is responsible for at least half of all hepatitis worldwide. Different viruses have been described with primary tropism for liver tissue. These microorganisms have been successively named with letters of the alphabet: A, B, C, D, E and G. The aim of this paper is to review this heterogeneous group of viruses in its most basic aspects, including clinical implications, treatment, main control, and prophylactic measures and, of special interest, diagnostic approaches, both serological and molecular, which are used for their detection, quantification and characterization.
肝脏炎症或肝炎有许多不同的病因,包括感染性和非感染性病因。在感染性病因中,病毒感染至少占全球所有肝炎病例的一半。已发现不同病毒对肝组织具有主要嗜性。这些微生物依次以字母表中的字母命名:A、B、C、D、E和G。本文旨在从最基本的方面对这一异质性病毒组进行综述,包括临床意义、治疗、主要控制措施和预防措施,特别值得关注的是用于病毒检测、定量和鉴定的血清学和分子诊断方法。