Bowden D S, Moaven L D, Locarnini S A
Victorian Infectious Diseases Reference Laboratory, Fairfield Hospital, Melbourne, VIC.
Med J Aust. 1996 Jan 15;164(2):87-9. doi: 10.5694/j.1326-5377.1996.tb101355.x.
Testing is now available for five recognised hepatitis viruses (A, B, C, D and E), and molecular technology is uncovering further hepatotropic viruses. An enteric agent isolated from human stool samples and transmitted experimentally to primates is a candidate hepatitis F virus. A provisionally designated blood-borne hepatitis G virus is associated with acute and chronic non-ABCDE hepatitis and has a worldwide distribution. A group of flavi-like viruses, the GB group, also blood borne, has also been reported. The role of two of these viruses, GBV-A and GBV-B, in human viral hepatitis has not been determined, but a third agent, GBV-C, is associated with acute and chronic hepatitis and appears to be a West African variant of hepatitis G. Our current knowledge suggests that the hepatitis alphabet may need to be extended even after inclusion of some of these new viruses.
目前可检测五种已确认的肝炎病毒（甲、乙、丙、丁和戊型），分子技术也发现了更多嗜肝病毒。从人类粪便样本中分离出并通过实验传播给灵长类动物的一种肠道病原体是庚型肝炎病毒的候选毒株。一种暂定为血源性传播的己型肝炎病毒与急慢性非甲、乙、丙、丁、戊型肝炎有关，且在全球范围内均有分布。还有一组黄病毒样病毒，即GB病毒组，同样通过血液传播。GBV - A和GBV - B这两种病毒在人类病毒性肝炎中的作用尚未确定，但第三种病毒GBV - C与急慢性肝炎有关，似乎是庚型肝炎的西非变种。我们目前的认知表明，即使纳入了这些新病毒中的一些，肝炎病毒的种类可能仍需扩充。
