Successful treatment of gastroparesis with the antidepressant mirtazapine: a case report.

Treatments for gastroparesis have been unsatisfactory. We describe a patient with gastroparesis who did not respond to a series of conventional prokinetic treatments. Finally, an antidepressant, mirtazapine, was administered, and the patient's symptoms and gastric emptying showed surprisingly rapid improvement. Therefore, we recommend mirtazapine as a treatment for gastroparesis refractory to conventional treatments.