Ardelean Melania, Sirli Roxana, Sporea Ioan, Bota Simona, Danila Mirela, Popescu Alina, Timar Bogdan, Buzas Roxana, Mazilu Octavian, Ardelean Ovidiu, Lighezan Daniel
Department of Gastroenterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
Department of Gastroenterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania. E-mail:
Med Ultrason. 2015 Mar;17(1):16-21. doi: 10.11152/mu.2013.2066.171.mars.
The AIM of our study was to evaluate the accuracy of CEUS in the characterization of pancreatic solid lesions, considering cross sectional imaging techniques (CE-CT/MRI) as the "gold standard" methods.
We performed a retrospective, monocentric study that included 91 solid pancreatic lesions which were evaluated by CEUS and by a second-line contrast imaging technique (CT or MRI), considered as the reference method.
The rate of a conclusive diagnosis based on a typical enhancement pattern was 94% (78/83 cases). In 72 cases out of 83 (86.7%) there was a perfect concordance between CEUS and the "gold-standard" imaging method (CE-CT/MRI). In our study, 88% (73/83) of the pancreatic lesions were categorized as malignant due to their typical wash-out aspect in the late phase. The overall accuracy of CEUS for the differential diagnosis of solid pancreatic tumors was approximately 81%. The accuracy of CEUS for the diagnosis of hypoenhancing pancreatic tumors was approximately 89.1%; while for the diagnosis of hyperenhancing pancreatic tumors it was approximately 72.8%.
CEUS allows the differentiation between hypo- vs. hyperenhancing pancreatic solid lesions, with a considerable diagnostic accuracy, a fundamental step in the precise diagnosis of pancreatic tumors.
本研究的目的是评估超声造影（CEUS）在胰腺实性病变特征描述中的准确性，将横断面成像技术（CE-CT/MRI）视为“金标准”方法。
我们进行了一项回顾性单中心研究，纳入了91例胰腺实性病变，这些病变通过CEUS和作为参考方法的二线对比成像技术（CT或MRI）进行评估。
基于典型增强模式得出确定性诊断的比例为94%（78/83例）。83例中有72例（86.7%）CEUS与“金标准”成像方法（CE-CT/MRI）完全一致。在我们的研究中，88%（73/83）的胰腺病变因其晚期典型的廓清表现被归类为恶性。CEUS对胰腺实性肿瘤鉴别诊断的总体准确性约为81%。CEUS对低增强胰腺肿瘤诊断的准确性约为89.1%；而对高增强胰腺肿瘤诊断的准确性约为72.8%。
CEUS能够区分低增强与高增强的胰腺实性病变，具有相当高的诊断准确性，这是胰腺肿瘤精确诊断的关键步骤。
