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对于患有食管闭锁和气管食管瘘的极低出生体重儿,低位食管束带术是一种挽救生命的做法,随后进行成功的延迟一期胸腔镜重建术。

Lower esophageal banding in extremely low birth weight infants with esophageal atresia and tracheoesophageal fistula is a life saving practice followed by a successful delayed primary thoracoscopy reconstruction.

作者信息

Margain Loren, Perez-Etchepare Eduardo, Varlet François, Lopez Manuel

机构信息

Department of Pediatric Surgery, University Hospital of Saint Etienne-France.

Department of Pediatric Surgery, University Hospital of Saint Etienne-France.

出版信息

J Pediatr Surg. 2015 Mar;50(3):489-92. doi: 10.1016/j.jpedsurg.2014.10.055. Epub 2014 Nov 20.

Abstract

In extremely low birth weight (ELBW) infants, i.e. <1000g, with esophageal atresia (EA) and tracheoesophageal fistula (TEF), surgical treatment is a real challenge. High morbidity is associated with primary repair of EA on these patients. We report our recent experience with three cases of ELBW infants with EA and TEF treated by lower esophageal banding (LEB). From September 2012 to January 2013, three ELBW infants with EA/TEF were born prematurely with severe respiratory distress. One of them had VACTER association with anorectal malformation (ARM). The gestational age was between 25 and 27weeks, and the mean birth weight was 690g (500-790). All were treated by LEB and gastrostomy, followed by delayed primary thoracoscopy reconstruction. One baby died in the postoperative period because of intraventricular hemorrhage at 7days after initial surgery. Among the 2 others cases, one of them required ligation without section of the TEF with removal of LEB by thoracoscopy at 30days old and 1300g. Delayed primary thoracoscopy reconstruction and section of TEF were performed by thoracoscopy at 70 and 80days old and 2100g and 2200g respectively without early complication. The follow-up was 12months. One baby presented a stenosis requiring one dilation of lower esophagus with uneventful course. LEB is a life saving practice in ELBW babies with EA and TEF. The esophagus can tolerate the ligation even with a thread without having a long time major complication. Thoracoscopic reconstruction of the esophagus is possible in these babies.

摘要

在极低出生体重(ELBW)婴儿中,即出生体重<1000g且患有食管闭锁(EA)和气管食管瘘(TEF)的婴儿,手术治疗是一项真正的挑战。对这些患者进行EA一期修复会伴随高发病率。我们报告了近期对3例ELBW且患有EA和TEF的婴儿采用低位食管束带术(LEB)治疗的经验。2012年9月至2013年1月,3例患有EA/TEF的ELBW婴儿早产并伴有严重呼吸窘迫。其中1例患有VACTER综合征并伴有肛门直肠畸形(ARM)。胎龄在25至27周之间,平均出生体重为690g(500 - 790g)。所有患儿均接受了LEB和胃造瘘术,随后进行延迟一期胸腔镜重建术。1例患儿在初次手术后7天因脑室内出血在术后死亡。在另外2例患儿中,其中1例在30日龄、体重1300g时需要进行TEF结扎但不切断,并通过胸腔镜移除LEB。分别在70日龄、体重2100g和80日龄、体重2200g时通过胸腔镜进行延迟一期胸腔镜重建术和TEF切断术,未出现早期并发症。随访时间为12个月。1例患儿出现狭窄,需要对下段食管进行1次扩张,过程顺利。LEB对于患有EA和TEF的ELBW婴儿是一种挽救生命的方法。食管即使使用丝线结扎也能耐受,且不会长期出现严重并发症。对这些婴儿进行胸腔镜食管重建术是可行的。

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