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极低出生体重儿(510 克,孕 25+5 周)合并食管闭锁并气管食管瘘的外科治疗:1 例报告。

Surgical treatment of esophageal atresia with lower tracheoesophageal fistula in an extremely preterm infant (510 g, 25 + 5 weeks): a case report.

机构信息

Department of Pediatric Surgery, University Hospital Leipzig, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.

Department of Neonatology, University Hospital Leipzig, University of Leipzig, Leipzig, Germany.

出版信息

J Med Case Rep. 2021 Jul 12;15(1):361. doi: 10.1186/s13256-021-02951-x.

Abstract

BACKGROUND

The surgical management of esophageal atresia in extreme-low-birth-weight infants (< 1000 g) is challenging. We report on an extreme-low-birth-weight infant who was extremely preterm (510 g, 25 + 5 weeks) and of prenatally unknown Gross type C esophageal atresia.

CASE PRESENTATION

After resuscitation and intubation, the tracheoesophageal fistula was closed on the first day of life in the neonatal intensive care unit via an extrapleural approach using a titanium clip. On the sixth day of life, the Caucasian child was extubated. To minimize the operative trauma in the initial neonatal period, we prolonged gastrostomy placement until the 22nd day of life (weight 725 g). At the age of 3 months (weight 2510 g), thoracoscopic esophageal anastomosis was performed. The postoperative course was unremarkable. During the further clinical course, eight esophageal dilations were necessary. Currently, the patient swallows without difficulties at the age of 4 years and thrives well [15 kg (Percentile 28); 100 cm (Percentile 24)].

CONCLUSIONS

Our case shows that minimized postnatal surgical trauma with primary tracheoesophageal fistula closure at the bedside, delayed gastrostomy, and minimally invasive esophageal repair after substantial weight gain (> 2.5 kg) is a good strategy for esophageal atresia/tracheoesophageal fistula in extreme-low-birth-weight infants.

摘要

背景

极低出生体重儿(<1000g)的食管闭锁手术处理极具挑战性。我们报告了一例极低出生体重儿(出生体重 510g,孕龄 25+5 周),产前食管闭锁类型未知为 Gross 分型 C 型。

病例介绍

患儿复苏后气管插管,于新生儿重症监护病房经胸腔外途径使用钛夹于生后第 1 天闭合气管食管瘘。生后第 6 天行气管拔管。为尽量减少新生儿期的手术创伤,我们将胃造口术延长至生后第 22 天(体重 725g)。3 月龄(体重 2510g)时行胸腔镜下食管吻合术。术后过程平稳。在进一步的临床病程中,患儿共进行了 8 次食管扩张。目前,患儿 4 岁时吞咽无困难,生长良好[15kg(百分位 28);100cm(百分位 24)]。

结论

我们的病例表明,对于极低出生体重儿的食管闭锁/气管食管瘘,采用床边最小化出生后手术创伤、一期气管食管瘘闭合、延迟胃造口术和体质量增加(>2.5kg)后微创食管修复是一种较好的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e6d/8273969/6e13aa8f1e4d/13256_2021_2951_Fig1_HTML.jpg

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