扩散加权成像与钆塞酸增强磁共振成像在肝细胞癌及乏血供肝细胞结节评估中的比较
Comparison of diffusion-weighted imaging and gadoxetic acid-enhanced MR images in the evaluation of hepatocellular carcinoma and hypovascular hepatocellular nodules.
作者信息
Di Pietropaolo Marco, Briani Chiara, Federici Giulia Francesca, Marignani Massimo, Begini Paola, Delle Fave Gianfranco, Iannicelli Elsa
机构信息
Radiology Unit, Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Radiology Unit, Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
出版信息
Clin Imaging. 2015 May-Jun;39(3):468-75. doi: 10.1016/j.clinimag.2014.12.020. Epub 2015 Jan 7.
PURPOSE
To compare diffusion-weighted imaging (DWI) and gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) magnetic resonance imaging (MRI) in the evaluation of hepatocellular carcinoma (HCC) and nodules at high risk of HCC transformation.
MATERIALS AND METHODS
We evaluated nodules' size, vascular pattern, and signal intensity on hepatobiliary phase images and on DWI of 105 nodules (41 cirrhotic patients).
RESULTS
A total of 35/66 HCCs identified on Gd-EOB-DTPA MRI showed hyperintensity on DWI. A total of 25/39 nodules (hypovascular and hypointense nodule on hepatobiliary phase images) progressed to HCC (higher risk for nodules ≥10mm in size and hyperintense on DWI, P<.05).
CONCLUSION
Gd-EOB-DTPA MRI demonstrated a significant role in the identification of nodule at higher risk of HCC transformation, and hyperintensity on DWI was associated with progression to HCC.
目的
比较扩散加权成像（DWI）和钆塞酸二钠（Gd-EOB-DTPA）磁共振成像（MRI）在评估肝细胞癌（HCC）及具有HCC转化高风险结节方面的作用。
材料与方法
我们评估了105个结节（41例肝硬化患者）在肝胆期图像及DWI上的结节大小、血管模式和信号强度。
结果
在Gd-EOB-DTPA MRI上识别出的66个HCC中，共有35个在DWI上表现为高信号。共有25/39个结节（在肝胆期图像上为低血供和低信号结节）进展为HCC（大小≥10mm且在DWI上为高信号的结节风险更高，P<0.05）。
结论
Gd-EOB-DTPA MRI在识别具有更高HCC转化风险的结节方面发挥了重要作用，DWI上的高信号与进展为HCC相关。
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