与来自灯源的图像相比，用于通过厚组织进行更深层成像的第二和第三近红外光学窗口中的近红外超连续激光束源。

Near-infrared supercontinuum laser beam source in the second and third near-infrared optical windows used to image more deeply through thick tissue as compared with images from a lamp source.

作者信息

Sordillo Laura A, Lindwasser Lukas, Budansky Yury, Leproux Philippe, Alfano Robert R

机构信息

City College of the City University of New York, Institute for Ultrafast Spectroscopy and Lasers, and Department of Physics, 160 Convent Avenue, New York, New York 10031, United States.

2XLIM-UMR CNRS 7252, Faculte des Sciences et Techniques, 123, Avenue Albert Thomas-87060 Limoges Cedex, France.

出版信息

J Biomed Opt. 2015 Mar;20(3):030501. doi: 10.1117/1.JBO.20.3.030501.

DOI:10.1117/1.JBO.20.3.030501

PMID:25748856

Abstract

With the use of longer near-infrared (NIR) wavelengths, image quality can be increased due to less scattering (described by the inverse wavelength power dependence 1/λ(n) where n ≥ 1 ) and minimal absorption from water molecules. Longer NIR windows, known as the second (1100 nm to 1350 nm) and third (1600 to 1870 nm) NIR windows are utilized to penetrate more deeply into tissue media and produce high-quality images. An NIR supercontinuum (SC) laser light source, with wavelengths in the second and third NIR optical windows to image tissue provides ballistic imaging of tissue. The SC ballistic beam can penetrate depths of up to 10 mm through tissue.

摘要

使用更长的近红外（NIR）波长时，由于散射较少（由逆波长幂依赖性1/λ(n)描述，其中n≥1）以及水分子的吸收最小，图像质量可以提高。更长的近红外窗口，即所谓的第二近红外窗口（1100纳米至1350纳米）和第三近红外窗口（1600至1870纳米），被用于更深入地穿透组织介质并产生高质量图像。一种近红外超连续谱（SC）激光光源，其波长在第二和第三近红外光学窗口内用于对组织成像，可提供组织的弹道成像。该超连续谱弹道光束可以穿透组织达10毫米的深度。