[Primary sclerosing cholangitis. A report of 2 cases and review of the literature].

Two cases are reported of primary sclerosing cholangitis (PSC) observed in the Institute of Gastroenterology of São Paulo-Brazil. These are presented together with a review of the relevant medical literature. Called our attention the delay for a definite diagnosis and the main symptoms that brought the patients to medical care. These were undoubtedly the progressive obstructive jaundice and severe pruritus. The role of the retrograde cholangio-pancreatography for definition of the diagnosis was presented.