[3-取代的1,2-苯并异恶唑及其抗精神病活性]
[3-substituted 1,2-benzisoxazole and their neuroleptic activity].
作者信息
Del Corona L, Signorelli G, Faini D, Pinzetta A, Coppi G
出版信息
Boll Chim Farm. 1989 May;128(5):177-81.
PMID:2574985
Abstract
The authors report the synthesis of two new derivatives of 3-substituted 1,2-benzisoxazole. The new molecules (P-1368, P-1370), evaluated in many pharmacological C.N.S. tests, show interesting neuroleptic activity but inferior to those of haloperidol and chlorpromazine.
摘要
作者报道了两种新的3-取代-1,2-苯并异恶唑衍生物的合成。新分子（P-1368、P-1370）在多项中枢神经系统药理学试验中进行了评估，显示出有趣的抗精神病活性，但低于氟哌啶醇和氯丙嗪。
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