Caignard D H, Couquelet J, Lesieur D, Lespagnol C, Lamar J C, Beaughard M, Leinot M, Tisne-Versailles J
Farmaco Sci. 1985 Nov;40(11):854-68.
Reaction of various amines on 6-(2-bromoethyl)benzoxazolinone or its N-methylated derivative provided eleven new 6-substituted aminoalkyl analogues. In a pharmacological evaluation, several compounds bearing an arylpiperazinic moiety were found to possess significant effects on arterial blood pressure and on the central nervous system; two of them showed interesting analgesic activity.