Serum free light chain trends between orthotopic heart transplantation and auto-SCT in patients with AL amyloidosis.

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作者信息

Renteria A S, Sanchorawala V, Niehaus E D, Sun F, Semigran M J, Seldin D C

机构信息

Amyloidosis Center, Boston University School of Medicine and Boston Medical Center, Boston, MA, USA.

Heart Failure and Cardiac Transplant Program, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.

出版信息

Bone Marrow Transplant. 2015 Jun;50(6):868-9. doi: 10.1038/bmt.2015.9. Epub 2015 Mar 9.

DOI:10.1038/bmt.2015.9

PMID:25751645

Abstract

摘要

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Safety and efficacy of high-dose melphalan and auto-SCT in patients with AL amyloidosis and cardiac involvement.高剂量美法仑和自体造血干细胞移植在伴有心脏受累的 AL 淀粉样变性患者中的安全性和疗效。

Bone Marrow Transplant. 2014 Mar;49(3):434-9. doi: 10.1038/bmt.2013.192. Epub 2013 Dec 9.

Predictors of survival to orthotopic heart transplant in patients with light chain amyloidosis.轻链淀粉样变性患者原位心脏移植生存的预测因素

J Heart Lung Transplant. 2014 Feb;33(2):149-56. doi: 10.1016/j.healun.2013.09.004. Epub 2013 Nov 5.

A European collaborative study of treatment outcomes in 346 patients with cardiac stage III AL amyloidosis.一项欧洲合作研究，对 346 例心脏 III 期 AL 淀粉样变患者的治疗结果进行了评估。

Blood. 2013 Apr 25;121(17):3420-7. doi: 10.1182/blood-2012-12-473066. Epub 2013 Mar 11.

Heart transplantation and cardiac amyloidosis: approach to screening and novel management strategies.心脏移植与心脏淀粉样变性：筛查方法与新的治疗策略。

J Heart Lung Transplant. 2012 Mar;31(3):325-31. doi: 10.1016/j.healun.2011.09.010. Epub 2011 Nov 3.

Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients.大剂量美法仑和自体干细胞移植后 AL 淀粉样变性的结果：一系列 421 例患者的长期结果。

Blood. 2011 Oct 20;118(16):4346-52. doi: 10.1182/blood-2011-01-330738. Epub 2011 Aug 9.

Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure.心脏移植后继以剂量密集美法仑和自体干细胞移植治疗轻链淀粉样变性和心力衰竭。

Transplantation. 2010 Oct 27;90(8):905-11. doi: 10.1097/TP.0b013e3181f10edb.

Autologous stem cell transplant after heart transplant for light chain (Al) amyloid cardiomyopathy.心脏移植后自体干细胞移植治疗轻链（AL）淀粉样心肌病。

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Sequential heart and autologous stem cell transplantation for systemic AL amyloidosis.序贯心脏与自体干细胞移植治疗系统性AL淀粉样变性

Blood. 2006 Feb 1;107(3):1227-9. doi: 10.1182/blood-2005-08-3253. Epub 2005 Oct 6.

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Progression of systemic disease and reduced long-term survival in patients with cardiac amyloidosis undergoing heart transplantation. Follow-up results of a multicenter survey.

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