Minneapolis VA Health Care System, Minneapolis, MN, USA; Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA.
Minneapolis VA Health Care System, Minneapolis, MN, USA; Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA.
Psychiatry Res. 2015 Apr 30;226(2-3):446-50. doi: 10.1016/j.psychres.2014.12.067. Epub 2015 Jan 28.
The goal of this epidemiological study was to investigate lifetime history and odds ratios of personality disorders in adopted and non-adopted adults using a nationally representative sample. Data, drawn from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC), were compared in adopted (n=378) versus non-adopted (n=42,503) adults to estimate the odds of seven personality disorders using logistic regression analyses. The seven personality disorders were histrionic, antisocial, avoidant, paranoid, schizoid, obsessive-compulsive, and dependent personality disorder. Adoptees had a 1.81-fold increase in the odds of any personality disorder compared with non-adoptees. Adoptees had increased odds of histrionic, antisocial, avoidant, paranoid, schizoid, and obsessive-compulsive personality disorder compared with non-adoptees. Two risk factors associated with lifetime history of a personality disorder in adoptees compared to non-adoptees were (1) being in the age cohort 18-29 years (but no difference in the age 30-44 cohort), using the age 45 or older cohort as the reference and (2) having 12 years of education (but no difference in higher education groups), using the 0-11 years of education as the reference. These findings support the higher rates of personality disorders among adoptees compared to non-adoptees.
本项流行病学研究旨在通过全国代表性样本，调查成年被领养者和非被领养者一生中的人格障碍史及其比值比。数据取自全国酒精相关条件流行病学调查（NESARC），在被领养者（n=378）与非被领养者（n=42,503）中进行比较，采用逻辑回归分析估计 7 种人格障碍的比值比。这 7 种人格障碍分别是：表演型、反社会型、回避型、偏执型、分裂型、强迫型和依赖型人格障碍。与非被领养者相比，被领养者发生任何一种人格障碍的几率增加了 1.81 倍。与非被领养者相比，被领养者发生表演型、反社会型、回避型、偏执型、分裂型和强迫型人格障碍的几率更高。与非被领养者相比，有两个因素与被领养者一生中发生人格障碍的风险相关：（1）年龄在 18-29 岁组（而在 30-44 岁组中没有差异），以 45 岁或以上年龄组为参照；（2）受教育 12 年（而在高教育群体中没有差异），以 0-11 年受教育程度为参照。这些发现支持被领养者比非被领养者更易发生人格障碍的观点。
