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New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor?单纯冠状动脉旁路移植术后新发心房颤动:肺动脉高压是危险因素吗?
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Does pulmonary hypertension affect early-term outcomes of off-pump coronary artery bypass surgery?肺动脉高压是否会影响非体外循环冠状动脉旁路移植术的早期结果?
Rev Assoc Med Bras (1992). 2022 Nov 25;68(12):1747-1752. doi: 10.1590/1806-9282.20220941. eCollection 2022.
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[The heart catheter table is not the operating table : Intraindividual comparison of pulmonary artery pressures].[心脏导管检查台并非手术台:肺动脉压的个体内比较]
Anaesthesist. 2018 May;67(5):351-358. doi: 10.1007/s00101-018-0431-8. Epub 2018 Apr 5.

本文引用的文献

1
The impact of preoperative and postoperative pulmonary hypertension on long-term surgical outcome after mitral valve repair for degenerative mitral regurgitation.术前和术后肺动脉高压对退行性二尖瓣反流二尖瓣修复术后长期手术结局的影响。
Ann Thorac Cardiovasc Surg. 2015;21(1):53-8. doi: 10.5761/atcs.oa.13-00364. Epub 2014 Apr 18.
2
Association of pre and intraoperative variables with postoperative complications in coronary artery bypass graft surgery.冠状动脉搭桥手术中术前和术中变量与术后并发症的关联
Rev Bras Cir Cardiovasc. 2013 Oct-Dec;28(4):518-23. doi: 10.5935/1678-9741.20130084.
3
Updated clinical classification of pulmonary hypertension.肺动脉高压的最新临床分类。
J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D34-41. doi: 10.1016/j.jacc.2013.10.029.
4
Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension.肺动脉高压右心和肺血管的代谢和生物能量学。
Pulm Circ. 2013 Jan;3(1):144-52. doi: 10.4103/2045-8932.109960.
5
Perioperative management of pulmonary hypertension.肺动脉高压的围手术期管理
Ann Card Anaesth. 2010 May-Aug;13(2):89-91. doi: 10.4103/0971-9784.62926.
6
Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT).肺动脉高压诊断和治疗指南:欧洲心脏病学会(ESC)和欧洲呼吸学会(ERS)肺动脉高压诊断和治疗工作组,得到国际心肺移植学会(ISHLT)认可。
Eur Heart J. 2009 Oct;30(20):2493-537. doi: 10.1093/eurheartj/ehp297. Epub 2009 Aug 27.
7
Pulmonary hypertension associated with left-sided heart disease.与左心疾病相关的肺动脉高压。
Clin Chest Med. 2007 Mar;28(1):233-41, x. doi: 10.1016/j.ccm.2006.12.001.
8
Atrial fibrillation after coronary artery bypass grafting in elderly patients: incidence and risk factor analysis.老年患者冠状动脉旁路移植术后房颤:发病率及危险因素分析
Thorac Cardiovasc Surg. 2007 Feb;55(1):32-8. doi: 10.1055/s-2006-924711.
9
Pulmonary arterial hypertension.肺动脉高压
N Engl J Med. 2004 Oct 14;351(16):1655-65. doi: 10.1056/NEJMra035488.
10
Ventilation prevents pulmonary endothelial dysfunction and improves oxygenation after cardiopulmonary bypass without aortic cross-clamping.通气可预防体外循环(无主动脉阻断)后的肺内皮功能障碍并改善氧合。
Eur J Cardiothorac Surg. 2004 Sep;26(3):554-63. doi: 10.1016/j.ejcts.2004.05.005.

肺动脉高压患者的冠状动脉搭桥手术:早期及长期结果评估

Coronary Bypass Surgery in Patients with Pulmonary Hypertension: Assessment of Early and Long Term Results.

作者信息

Akca Baris, Erdil Nevzat, Disli Olcay Murat, Donmez Koksal, Erdil Feray, Colak Mehmet Cengiz, Battaloglu Bektas

机构信息

Department of Cardiovascular Surgery, Inonu University Faculty of Medicine, Malatya, Turkey.

出版信息

Ann Thorac Cardiovasc Surg. 2015;21(3):268-74. doi: 10.5761/atcs.oa.14-00227. Epub 2015 Mar 9.

DOI:10.5761/atcs.oa.14-00227
PMID:25753326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4989974/
Abstract

PURPOSE

We aimed to evaluate the effects of preoperative pulmonary hypertension (PH) on early and long term results in patients undergoing coronary bypass surgery and the effects of coronary bypass surgery on PH.

METHODS

Among 2325 patients who underwent elective isolated coronary artery bypass surgery between March 2003 and March 2012, 287 patients with high preoperative pulmonary arterial pressure (PAP) ≥30 mmHg were examined. Patients' data were obtained by retrospective examination of our clinic's database. 69 patients who had complete parameters included in the study.

RESULTS

There was no increase in the New York Heart Association (NYHA) functional classification 84% of cases. Preoperative and postoperative values of the mean ejection fraction and mean PAP of patients was respectively 45.28 ± 9.67 (25-65), 46.03 ±12.4 (20-65) (p = 0.447), 36.67 ± 6.81 (30-60) mmHg, 37.81 ± 10.07 (20-70) mmHg (p = 0.378). The late mortality of cases was 5.79%. In our study, during 33.9 ± 17 (9-100) months follow up period, life expectancy was calculated as 94.7 months.

CONCLUSION

Preoperative evaluation of these patients for appropriate medical treatment at peroperative and postoperative period, coronary bypass can be performed with low morbidity and mortality rates. In the late period after surgical revascularization PH showed no significant change and had no adverse effect on quality of life.

摘要

目的

我们旨在评估术前肺动脉高压(PH)对接受冠状动脉搭桥手术患者的早期和长期结果的影响,以及冠状动脉搭桥手术对PH的影响。

方法

在2003年3月至2012年3月期间接受择期单纯冠状动脉搭桥手术的2325例患者中,检查了287例术前肺动脉压(PAP)≥30 mmHg的患者。通过回顾性检查我们诊所的数据库获得患者数据。69例具有完整参数的患者纳入研究。

结果

84%的病例纽约心脏协会(NYHA)功能分级没有增加。患者术前和术后的平均射血分数和平均PAP值分别为45.28±9.67(25 - 65)、46.03±12.4(20 - 65)(p = 0.447),36.67±6.81(30 - 60)mmHg,37.81±10.07(20 - 70)mmHg(p = 0.378)。病例的晚期死亡率为5.79%。在我们的研究中,在33.9±17(9 - 100)个月的随访期内,计算出的预期寿命为94.7个月。

结论

对这些患者进行术前评估以便在围手术期和术后进行适当的药物治疗,冠状动脉搭桥手术可以在低发病率和死亡率的情况下进行。在手术血运重建后的后期,PH没有显著变化,对生活质量也没有不良影响。