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肺动脉高压患者的冠状动脉搭桥手术:早期及长期结果评估

Coronary Bypass Surgery in Patients with Pulmonary Hypertension: Assessment of Early and Long Term Results.

作者信息

Akca Baris, Erdil Nevzat, Disli Olcay Murat, Donmez Koksal, Erdil Feray, Colak Mehmet Cengiz, Battaloglu Bektas

机构信息

Department of Cardiovascular Surgery, Inonu University Faculty of Medicine, Malatya, Turkey.

出版信息

Ann Thorac Cardiovasc Surg. 2015;21(3):268-74. doi: 10.5761/atcs.oa.14-00227. Epub 2015 Mar 9.

Abstract

PURPOSE

We aimed to evaluate the effects of preoperative pulmonary hypertension (PH) on early and long term results in patients undergoing coronary bypass surgery and the effects of coronary bypass surgery on PH.

METHODS

Among 2325 patients who underwent elective isolated coronary artery bypass surgery between March 2003 and March 2012, 287 patients with high preoperative pulmonary arterial pressure (PAP) ≥30 mmHg were examined. Patients' data were obtained by retrospective examination of our clinic's database. 69 patients who had complete parameters included in the study.

RESULTS

There was no increase in the New York Heart Association (NYHA) functional classification 84% of cases. Preoperative and postoperative values of the mean ejection fraction and mean PAP of patients was respectively 45.28 ± 9.67 (25-65), 46.03 ±12.4 (20-65) (p = 0.447), 36.67 ± 6.81 (30-60) mmHg, 37.81 ± 10.07 (20-70) mmHg (p = 0.378). The late mortality of cases was 5.79%. In our study, during 33.9 ± 17 (9-100) months follow up period, life expectancy was calculated as 94.7 months.

CONCLUSION

Preoperative evaluation of these patients for appropriate medical treatment at peroperative and postoperative period, coronary bypass can be performed with low morbidity and mortality rates. In the late period after surgical revascularization PH showed no significant change and had no adverse effect on quality of life.

摘要

目的

我们旨在评估术前肺动脉高压(PH)对接受冠状动脉搭桥手术患者的早期和长期结果的影响,以及冠状动脉搭桥手术对PH的影响。

方法

在2003年3月至2012年3月期间接受择期单纯冠状动脉搭桥手术的2325例患者中,检查了287例术前肺动脉压(PAP)≥30 mmHg的患者。通过回顾性检查我们诊所的数据库获得患者数据。69例具有完整参数的患者纳入研究。

结果

84%的病例纽约心脏协会(NYHA)功能分级没有增加。患者术前和术后的平均射血分数和平均PAP值分别为45.28±9.67(25 - 65)、46.03±12.4(20 - 65)(p = 0.447),36.67±6.81(30 - 60)mmHg,37.81±10.07(20 - 70)mmHg(p = 0.378)。病例的晚期死亡率为5.79%。在我们的研究中,在33.9±17(9 - 100)个月的随访期内,计算出的预期寿命为94.7个月。

结论

对这些患者进行术前评估以便在围手术期和术后进行适当的药物治疗,冠状动脉搭桥手术可以在低发病率和死亡率的情况下进行。在手术血运重建后的后期,PH没有显著变化,对生活质量也没有不良影响。

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