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多发性扁平苔藓样角化病:类苔藓样药疹模拟物及老年人瘙痒性皮疹未被充分认识的病因。

Multiple lichen planus-like keratoses: Lichenoid drug eruption simulant and under-recognised cause of pruritic eruptions in the elderly.

作者信息

Pitney Lucy, Weedon David, Pitney Michael

机构信息

RMO, Nambour Hospital, Nambour, Queensland, Australia.

Sullivan Nicolaides Patholology, Brisbane, Queensland, Australia.

出版信息

Australas J Dermatol. 2016 Feb;57(1):54-6. doi: 10.1111/ajd.12288. Epub 2015 Mar 5.

DOI:10.1111/ajd.12288
PMID:25753682
Abstract

We present six cases of multiple eruptive lichen planus-like keratoses (LPLK), occurring in older individuals predominately confined to previously solar exposed areas. Diagnosis was often confounded by the frequent histological reporting of 'lichenoid drug reaction' (LDR), despite many of the patients being unmedicated. We review the literature regarding eruptive LPLK and reflect on their etiology, clinical aspects, management and importantly their clinicopathological differentiation from LDR.

摘要

我们报告了6例多发性发疹性扁平苔藓样角化病(LPLK),发生于老年个体,主要局限于先前暴露于日光的部位。尽管许多患者未用药,但诊断常因频繁的组织学报告为“苔藓样药物反应”(LDR)而混淆。我们回顾了有关发疹性LPLK的文献,并思考了它们的病因、临床特征、管理,以及重要的是它们与LDR的临床病理鉴别。

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