Payette Michael J, Weston Gillian, Humphrey Stephen, Yu JiaDe, Holland Kristen E
Department of Dermatology, University of Connecticut Health Center, 21 South Road, Second Floor, Farmington, CT 06032.
University of Connecticut School of Medicine, 263 Farmington Ave, Farmington, CT 06030.
Clin Dermatol. 2015 Nov-Dec;33(6):631-43. doi: 10.1016/j.clindermatol.2015.09.006. Epub 2015 Sep 12.
Lichenoid dermatoses, a group of inflammatory skin conditions with characteristic clinical and histopathologic findings, range from common to rare. Classic lichen planus typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist. Other lichenoid dermatoses share similar clinical presentations and histopathologic findings. These include lichenoid drug eruption, lichen planus-like keratosis, lichen striatus, lichen nitidus, and keratosis lichenoides chronica. Epidemiologic characteristics vary among each lichenoid disorder. While classic lichen planus is considered a disease of adults, other lichenoid dermatoses may be more common in younger populations. The literature contains an array of reports on the variations in presentation and successful management of lichen planus and lichenoid dermatoses among diverse populations. Familiarity with the characteristics of each lichenoid dermatosis, rare or common within each patient population, is key to accomplishing timely recognition and effective management.
苔藓样皮肤病是一组具有特征性临床和组织病理学表现的炎症性皮肤病,从常见到罕见不等。经典扁平苔藓通常表现为瘙痒性、多边形、紫罗兰色的扁平丘疹和斑块;在形态和部位上也存在许多变体。其他苔藓样皮肤病具有相似的临床表现和组织病理学表现。这些包括苔藓样药物疹、扁平苔藓样角化病、线状苔藓、光泽苔藓和慢性苔藓样角化病。每种苔藓样疾病的流行病学特征各不相同。虽然经典扁平苔藓被认为是一种成人疾病,但其他苔藓样皮肤病在年轻人群中可能更为常见。文献中有一系列关于不同人群中扁平苔藓和苔藓样皮肤病表现差异及成功治疗的报道。熟悉每种苔藓样皮肤病的特征,无论在每个患者群体中是罕见还是常见,是实现及时识别和有效治疗的关键。