Cellard Caroline, Reeder Clare, Paradis-Giroux Andrée-Anne, Roy Marc-André, Gilbert Elsa, Ivers Hans, Bouchard Roch-Hugo, Maziade Michel, Wykes Til
a École de psychologie , Université Laval , Québec , Canada.
b Centre de recherche de l'Institut universitaire en santé mentale de Québec , Québec , Canada.
Neuropsychol Rehabil. 2016;26(3):321-44. doi: 10.1080/09602011.2015.1019891. Epub 2015 Mar 10.
Cognitive remediation therapy is effective for improving cognition, symptoms and social functioning in individuals with schizophrenia; however, the impact on visual episodic memory remains unclear. The objectives of this feasibility study were: (1) to explore whether or not CIRCuiTS--a new computerised cognitive remediation therapy programme developed in England--improves visual episodic memory and other cognitive domains in young adults with early course schizophrenia; and (2) to evaluate acceptability of the CIRCuiTS programme in French-Canadians. Three participants with visual episodic memory impairments at baseline were recruited from clinical settings in Canada, and consented to participate. Neuropsychological, clinical and social functioning was evaluated at baseline and post-treatment. Intervention involved 40 sessions of cognitive remediation. First, the reliable change index (RCI) revealed that each participant demonstrated significant post-therapy change in episodic memory and in other cognitive domains. The response profile was characterised by the use of organisational strategies. Second, the treatment was considered acceptable to participants in terms of session frequency (number of sessions per week), intensity (hours per week; total hours), and number of missed sessions and total completed sessions. This preliminary study yielded encouraging data demonstrating the feasibility of the CIRCuiTS programme in French-Canadian young adults with schizophrenia.
认知康复治疗对于改善精神分裂症患者的认知、症状及社会功能有效；然而，其对视觉情景记忆的影响仍不明确。本可行性研究的目的为：（1）探究CIRCuiTS（一项在英国开发的新型计算机化认知康复治疗项目）是否能改善早期精神分裂症青年患者的视觉情景记忆及其他认知领域；（2）评估CIRCuiTS项目在法裔加拿大人中的可接受性。从加拿大临床机构招募了3名基线时存在视觉情景记忆损伤的参与者，并征得其同意参与研究。在基线和治疗后对神经心理学、临床及社会功能进行评估。干预包括40节认知康复治疗课程。首先，可靠变化指数（RCI）显示，每位参与者在情景记忆及其他认知领域均表现出显著的治疗后变化。反应特征表现为使用组织策略。其次，从疗程频率（每周疗程数）、强度（每周小时数；总小时数）、错过疗程数及完成的总疗程数来看，参与者认为该治疗是可接受的。这项初步研究得出了令人鼓舞的数据，证明了CIRCuiTS项目在法裔加拿大精神分裂症青年患者中的可行性。
