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剖宫产术后早期经口喂养与延迟经口喂养的比较:一项荟萃分析。

Early oral feeding compared with delayed oral feeding after cesarean section: a meta-analysis.

作者信息

Huang Huaping, Wang Haiyan, He Mei

机构信息

a Department of Nursing Administration , Mianyang Central Hospital , Sichuan , China.

出版信息

J Matern Fetal Neonatal Med. 2016;29(3):423-9. doi: 10.3109/14767058.2014.1002765. Epub 2015 Mar 10.

Abstract

AIM

The potential benefits and safety of early oral feeding (EOF) after cesarean section have not been well evaluated. We undertook a meta-analysis to assess postoperative bowel function and complications following EOF compared with delayed oral feeding (DOF) in women who had undergone cesarean section.

METHODS

PubMed, EMBASE, and CENTRAL were searched to identify English language randomized clinical trials comparing EOF with DOF after cesarean section. The primary outcomes of interest were bowel motility and postoperative complications. The random-effect model was used to calculate pooled weighted mean differences (WMDs) and relative risks (RRs), with 95% confidence intervals (CIs).

RESULTS

Eleven studies involving 1800 patients were included. The pooled results showed that EOF was significantly associated with the shorter time to return of bowel motility compared with DOF (-7.3 h for passage of flatus; -6.27 h for bowel movement; -8.75 h for bowel sounds). EOF was not related to increases in nausea (RR, 0.95; 95% CI, 0.69-1.33), abdominal distension (RR, 0.68; 95% CI, 0.43-1.07), diarrhea (RR, 0.63; 95% CI, 0.28-1.41), mild ileus symptoms (RR, 0.82; 95% CI, 0.53-1.25) and vomiting (RR, 0.91; 95% CI, 0.53-1.56).

CONCLUSIONS

This meta-analysis provides evidence that EOF after cesarean section enhances the return of bowel function and does not increase the risk of postoperative complications.

摘要

目的

剖宫产术后早期经口进食(EOF)的潜在益处和安全性尚未得到充分评估。我们进行了一项荟萃分析,以评估剖宫产术后EOF与延迟经口进食(DOF)相比的术后肠道功能和并发症情况。

方法

检索了PubMed、EMBASE和CENTRAL数据库,以识别比较剖宫产术后EOF与DOF的英文随机临床试验。主要关注的结局是肠道蠕动和术后并发症。采用随机效应模型计算合并加权平均差(WMDs)和相对风险(RRs),并给出95%置信区间(CIs)。

结果

纳入了11项涉及1800例患者的研究。汇总结果显示,与DOF相比,EOF与肠道蠕动恢复时间显著缩短相关(排气时间缩短7.3小时;排便时间缩短6.27小时;肠鸣音恢复时间缩短8.75小时)。EOF与恶心(RR,0.95;95%CI,0.69-1.33)、腹胀(RR,0.68;95%CI,0.43-1.07)、腹泻(RR,0.63;95%CI,0.28-1.41)、轻度肠梗阻症状(RR,0.82;95%CI,0.53-1.25)和呕吐(RR,0.91;95%CI,0.53-1.56)的增加无关。

结论

这项荟萃分析提供了证据,表明剖宫产术后EOF可促进肠道功能恢复,且不会增加术后并发症的风险。

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