Ciardulli Andrea, Saccone Gabriele, Di Mascio Daniele, Caissutti Claudia, Berghella Vincenzo
a Department of Obstetrics and Gynecology , Catholic University of Sacred Heart , Rome , Italy.
b Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine , University of Naples Federico II , Naples , Italy.
J Matern Fetal Neonatal Med. 2018 Jul;31(14):1924-1932. doi: 10.1080/14767058.2017.1330883. Epub 2017 Jun 6.
OBJECTIVE: To examine whether chewing gum hastens the return of gastrointestinal function after a cesarean delivery. METHODS: All randomized controlled trials comparing the use of chewing gum in the immediate postoperative recovery period (i.e. intervention group) with a control group were included in the meta-analysis. The primary outcome was the time to first flatus in hours. Meta-analysis was performed using the random effects model of DerSimonian and Laird, to produce summary treatment effects in terms of mean difference (MD) or relative risk (RR) with 95% confidence interval (CI). RESULTS: Seventeen trials, including 3041 women, were analyzed. Trials were of moderate to low quality with different inclusion criteria. In most of the included trials chewing gum was given right after delivery, three times a day for 30 min each and until the first flatus. Women who were randomized to the chewing gum group had a significantly lower mean time to first flatus (MD - 6.49 h, 95%CI -8.65 to -4.33), to first bowel sounds (MD - 8.48 h, 95%CI -9.04 to -7.92), less duration of stay (MD - 0.39 days, 95%CI -0.78 to -0.18), lower time to first feces (MD - 9.57 h, 95% CI -10.28 to 8.87) and to the first feeling of hunger (MD - 2.89 h, 95%CI -4.93 to -0.85), less number of episodes of nausea or vomiting (RR 0.33, 95%CI 0.12 to 0.87), less incidence of ileus (RR 0.39, 95%CI 0.19 to 0.80) and significantly higher satisfaction. CONCLUSIONS: Gum chewing starting right after cesarean delivery three times a day for about 30 min until the first flatus is associated with early recovery of bowel motility. As this is a simple, generally inexpensive intervention, providers should consider implementing cesarean postoperative care with gum chewing.
目的:探讨剖宫产术后嚼口香糖是否能加速胃肠功能恢复。 方法:纳入所有比较术后即刻(即干预组)嚼口香糖与对照组的随机对照试验进行荟萃分析。主要结局指标为首次排气时间(小时)。采用DerSimonian和Laird随机效应模型进行荟萃分析,以均数差(MD)或相对危险度(RR)及95%置信区间(CI)得出汇总治疗效应。 结果:分析了17项试验,共3041名女性。试验质量为中到低,纳入标准各异。在大多数纳入试验中,产后即给予嚼口香糖,每天3次,每次30分钟,直至首次排气。随机分配到嚼口香糖组的女性首次排气平均时间显著缩短(MD - 6.49小时,95%CI -8.65至-4.33),首次肠鸣音时间(MD - 8.48小时,95%CI -9.04至-7.92),住院时间缩短(MD - 0.39天,95%CI -0.78至-0.18),首次排便时间缩短(MD - 9.57小时,95%CI -10.28至8.87),首次有饥饿感时间缩短(MD - 2.89小时,95%CI -4.93至-0.85),恶心或呕吐发作次数减少(RR 0.33,95%CI 0.12至0.87),肠梗阻发生率降低(RR 0.39,95%CI 0.19至0.80),满意度显著提高。 结论:剖宫产术后即刻开始每天嚼口香糖3次,每次约30分钟,直至首次排气,与肠道运动早期恢复相关。由于这是一种简单且通常成本低廉的干预措施,医疗服务提供者应考虑在剖宫产术后护理中采用嚼口香糖的方法。
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