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局部用皮质类固醇的眼部副作用:皮肤科医生需要了解的内容。

Ocular side-effects of topical corticosteroids: what a dermatologist needs to know.

作者信息

Daniel Benjamin S, Orchard David

机构信息

Dermatology Department, Royal Children's Hospital, Melbourne, Victoria, Australia.

Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

出版信息

Australas J Dermatol. 2015 Aug;56(3):164-9. doi: 10.1111/ajd.12292. Epub 2015 Mar 5.

Abstract

Topical corticosteroids are used frequently in dermatology and atopic dermatitis without significant adverse effects. Though ocular diseases such as glaucoma and cataracts are known complications of systemic corticosteroids, the role of topical corticosteroids is limited to case reports. This review assesses the literature regarding topical steroids and their role in ocular diseases. There is evidence of harm to vision when potent topical corticosteroids are inappropriately used for prolonged periods to periorbital sites. There is no evidence to date that weak TCS to the face or potent TCS to areas other than the eyes results in ocular complications. Further research trials are required in this area.

摘要

局部用皮质类固醇激素在皮肤科和特应性皮炎中经常使用,且无明显不良反应。虽然青光眼和白内障等眼部疾病是全身性皮质类固醇激素已知的并发症,但局部用皮质类固醇激素的作用仅限于病例报告。本综述评估了关于局部用类固醇激素及其在眼部疾病中作用的文献。有证据表明,强效局部用皮质类固醇激素长时间不适当地用于眶周部位会损害视力。迄今为止,尚无证据表明面部使用弱效局部用皮质类固醇激素或眼部以外部位使用强效局部用皮质类固醇激素会导致眼部并发症。该领域需要进一步的研究试验。

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