Melkikh Alexey V
Ural Federal University, Yekaterinburg, Russia, Mira str. 19,
Orig Life Evol Biosph. 2015 Jun;45(1-2):163-71. doi: 10.1007/s11084-015-9414-9. Epub 2015 Mar 11.
Two of the most fundamental questions concerning the origin of life, how biologically important molecules (RNA, proteins) find their unique spatial configuration, and how coding sequences can evolve beyond a certain critical length, are discussed. It is shown that both of these problems have not been solved. Experiments that could clarify the mechanisms of interaction between biologically important molecules in the simplest cells are discussed.
具有生物学重要性的分子（RNA、蛋白质）如何找到其独特的空间构型，以及编码序列如何进化到超过某个临界长度。结果表明，这两个问题都尚未得到解决。文中还讨论了能够阐明最简单细胞中具有生物学重要性的分子之间相互作用机制的实验。
