Melkikh Alexey V
Ural Federal University, Mira str. 19, Yekaterinburg 620002, Russia.
Biosystems. 2014 May;119:10-9. doi: 10.1016/j.biosystems.2014.03.005. Epub 2014 Apr 2.
The problem of processing and transmitting information within neurons is considered. The fundamental paradox of molecular biology is formulated, namely that interactions between biologically important molecules should lead to an exponentially large number of variants of molecular structures, but only a small number of them are biologically relevant. The problem is that the known interaction potentials between atoms do not allow this. The solution of the paradox, based on the nonlinear quantum model of interaction between biologically important molecules, is proposed. The model includes a nonlinear equation for many-particle nonlocal potential describing this interaction. Under the action of this potential there occurs the formation of synaptic connections between neurons, and transport processes and molecular recognition inside neurons. The information on which programs of innate behavior operate is hypothesized to reside in the quantum degrees of freedom of the proposed potential. Possible experiments to test the model are proposed.
本文探讨了神经元内部信息处理与传输的问题。阐述了分子生物学的基本悖论,即生物重要分子间的相互作用应产生指数级数量的分子结构变体,但其中只有少数具有生物学相关性。问题在于已知的原子间相互作用势无法实现这一点。基于生物重要分子间相互作用的非线性量子模型,提出了该悖论的解决方案。该模型包含一个用于描述这种相互作用的多粒子非局域势的非线性方程。在这种势的作用下,神经元之间会形成突触连接,同时神经元内部会发生传输过程和分子识别。推测先天行为程序所依据的信息存在于所提出势的量子自由度中。还提出了检验该模型的可能实验。