Wingate-Saul L, Rymer J, Greaves M W
Guy's and St Thomas' NHS Foundation Trust, London, UK.
Clin Exp Dermatol. 2015 Aug;40(6):644-6. doi: 10.1111/ced.12632. Epub 2015 Mar 9.
A 23-year-old, regularly menstruating woman presented with recurrent urticarial eruptions, which occurred premenstrually. A skin prick test was positive for progesterone, but the urticaria was unresponsive to standard treatments. The patient was treated with goserelin (Zoladex), which suppressed her menstrual cycle, leading to the resolution of her symptoms. Subsequent flares were controlled by further goserelin injections, and the urticaria is currently in remission. However, the risks of inducing menopause artificially are significant, and alternative long-term solutions may need to be considered in the event of a relapse.
一名23岁月经规律的女性出现反复的荨麻疹皮疹，这些皮疹在月经前出现。皮肤点刺试验显示对孕酮呈阳性反应，但荨麻疹对标准治疗无反应。该患者接受了戈舍瑞林（诺雷德）治疗，这抑制了她的月经周期，使症状得到缓解。随后的发作通过进一步注射戈舍瑞林得到控制，目前荨麻疹处于缓解期。然而，人为诱导绝经的风险很大，如果复发，可能需要考虑其他长期解决方案。
