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Localization of two alkaline phosphatase genes to the proximal region of mouse chromosome 1.

作者信息

Schurr E, Henthorn P S, Harris H, Skamene E, Gros P

机构信息

Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

出版信息

Cytogenet Cell Genet. 1989;52(1-2):65-7. doi: 10.1159/000132841.

Abstract

Using a human cDNA clone encoding the intestinal form of alkaline phosphatase, we have identified and mapped by RFLP analysis in a Mus spretus x C57BL/6J interspecies backcross two alkaline phosphatase genes which segregate independently on the proximal part of mouse Chromosome 1. The gene order and intergene distances were determined by standard backcross analysis as: centromere- Len-2 - 19.0 cM - Akp-3 - 20.0 cM - Akp-4 - 2.0 cM - Ren-1.

摘要

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