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监测在肝细胞癌预防中的作用。

Role of surveillance in prevention of hepatocellular carcinoma.

作者信息

Panda Dipanjan

机构信息

Department of Medical Oncology, Institute of Liver and Biliary Sciences, D1 Vasant Kunj, New Delhi 110014, India.

出版信息

J Clin Exp Hepatol. 2014 Aug;4(Suppl 3):S43-9. doi: 10.1016/j.jceh.2014.03.044. Epub 2014 May 25.

Abstract

Hepatocellular carcinoma is a common malignancy and one of the important public health problems in India. The surveillance of hepatocellular carcinoma (HCC) is an established approach to detect early cancers in patients with defined risks. However, there are still controversies and issues to be addressed regarding the optimal surveillance methods and interval. The current level of awareness among physicians in India about surveillance is low and the need and most cost effective surveillance strategy in developing country like ours is unclear. This article has tried to discuss these issues in their appropriate perspective. To address this complicated issue, a multicenter randomized prospective study however may be required.

摘要

肝细胞癌是一种常见的恶性肿瘤,也是印度重要的公共卫生问题之一。肝细胞癌(HCC)的监测是在具有明确风险的患者中检测早期癌症的既定方法。然而,关于最佳监测方法和间隔时间仍存在争议和问题有待解决。印度医生目前对监测的认识水平较低,在像我们这样的发展中国家,需求和最具成本效益的监测策略尚不清楚。本文试图从适当的角度讨论这些问题。然而,为了解决这个复杂的问题,可能需要进行一项多中心随机前瞻性研究。

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本文引用的文献

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Failure rates in the hepatocellular carcinoma surveillance process.肝癌监测过程中的失败率。
Cancer Prev Res (Phila). 2012 Sep;5(9):1124-30. doi: 10.1158/1940-6207.CAPR-12-0046. Epub 2012 Jul 30.
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Cancer mortality in India: a nationally representative survey.印度的癌症死亡率:一项全国代表性调查。
Lancet. 2012 May 12;379(9828):1807-16. doi: 10.1016/S0140-6736(12)60358-4. Epub 2012 Mar 28.
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Effectiveness of hepatocellular carcinoma surveillance in patients with cirrhosis.肝硬化患者肝癌监测的效果。
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