Pan Fuwen, Liu Qiang, Zhang Guoru, Wang Qiqi, Yun Bo, Han Yaoguang, Deng Rui, Wu Linqing, Wang Shihua
Department of Orthopedics, Hainan Province Nongken Sanya Hospital 146 Jiefang 4th Road, Sanya 572000, Hainan Province, China.
Department of Pathology, Hainan Province Nongken Sanya Hospital 146 Jiefang 4th Road, Sanya 572000, Hainan Province, China.
Int J Clin Exp Pathol. 2015 Jan 1;8(1):948-53. eCollection 2015.
Aggressive fibromatosis is a rare soft tissue tumor that composes of myofibroblasts that arise from musculoaponeurotic structures. It usually affects the abdominal wall but may be also found in other less common sites including the head and neck, submucosa of the oral cavity, spinal, haunch and limbs, especially, the limbs and sacrococcygeal region are rare locations. We described two cases of aggressive fibromatosis. One was 3-year-old girl with aggressive fibromatosis arising from the right leg region. The other was 20-year-old female arising from in the sacrococcygeal region. They were resected with satisfied results. Pathological examination showed that they were composed of fibroblasts, fibrocytes and bundles of collagen fiber. The aggressive fibromatosis, although rare, should be differentiated from some other soft tissue tumors with similar histological features and different localizations of intra-abdominal, abdominal wall and extra-abdominal.
侵袭性纤维瘤病是一种罕见的软组织肿瘤，由起源于肌筋膜结构的肌成纤维细胞组成。它通常累及腹壁，但也可能出现在其他不太常见的部位，包括头颈部、口腔黏膜下层、脊柱、臀部和四肢，尤其是四肢和骶尾部是罕见部位。我们报告了两例侵袭性纤维瘤病病例。一例是一名3岁女童，侵袭性纤维瘤病起源于右下肢区域。另一例是一名20岁女性，起源于骶尾部。她们均接受了手术切除，效果满意。病理检查显示，肿瘤由成纤维细胞、纤维细胞和胶原纤维束组成。侵袭性纤维瘤病虽然罕见，但应与其他一些具有相似组织学特征但部位不同（腹腔内、腹壁和腹腔外）的软组织肿瘤相鉴别。
