Mediannikov O, Aubadie-Ladrix M, Raoult D
Aix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE) UM63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France ; Aix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE) UM63, CNRS 7278, IRD 198, Inserm 1095, Dakar, Senegal.
Aix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE) UM63, CNRS 7278, IRD 198, Inserm 1095, Dakar, Senegal.
New Microbes New Infect. 2014 Nov 8;3:24-8. doi: 10.1016/j.nmni.2014.10.005. eCollection 2015 Jan.
Epidemiological studies of Rickettsia felis and related bacteria are very important, because the natural cycle of this important infection has not yet been established. The recent emergence of R. felis-associated febrile diseases in West and East Africa demands insightful epidemiological studies of the vectors and reservoirs of this bacterium in Africa. Twenty-nine cat fleas, Ctenocephalides felis, were tested for the presence of rickettsiae, including R. felis, bartonellae, and borreliae, with specific quantitative real-time PCR assays. Supporting our previous studies, R. felis was not detected in the fleas collected. In addition, neither Bartonella nor Borrelia was found. In five (17%) examined fleas, we found another species of rickettsia. We isolated three rickettsial strains, and genetic analysis demonstrated that these strains represent a probable new species, provisionally called Candidatus Rickettsia senegalensis here.
对猫立克次氏体及相关细菌进行流行病学研究非常重要，因为这种重要感染的自然循环尚未明确。近期在西非和东非出现了与猫立克次氏体相关的发热性疾病，这就需要对非洲该细菌的传播媒介和宿主进行有深度的流行病学研究。我们采用特异性定量实时聚合酶链反应检测法，对29只猫栉首蚤进行了立克次氏体检测，包括猫立克次氏体、巴尔通体和疏螺旋体。与我们之前的研究结果一致，在所采集的跳蚤中未检测到猫立克次氏体。此外，也未发现巴尔通体和疏螺旋体。在5只（17%）接受检测的跳蚤中，我们发现了另一种立克次氏体。我们分离出了三株立克次氏体菌株，基因分析表明这些菌株可能代表一个新物种，在此暂称为“塞内加尔立克次氏体候选种”。
