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在一名预定进行牙髓治疗的患者中，意外注射了次氯酸钠而非局部麻醉剂。

Accidental injection of sodium hypochlorite instead of local anesthetic in a patient scheduled for endodontic procedure.

作者信息

Waknis Pushkar Prakash, Deshpande Aditya Sunil, Sabhlok Samrat

机构信息

Professor, Dr. DY Patil Dental College, Pune and Consultant Maxillofacial Surgeon, Deenanath Mangeshkar Hospital, Pune.

Research Associate, Deenanath Mangeshkar Hospital, Pune.

出版信息

J Oral Biol Craniofac Res. 2011 Oct-Dec;1(1):50-2. doi: 10.1016/S2212-4268(11)60013-4.

DOI:10.1016/S2212-4268(11)60013-4
PMID:25756020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3941633/
Abstract

We present here a case of tissue destruction and paresthesia following the accidental injection of sodium hypochlorite instead of local anesthetic in a patient scheduled for endodontic procedure. The accident was managed by the local injection of steroid, debridement of necrotic tissue, daily dressings and medications. Wound healing was satisfactory at the end of 1 month. An extra-oral scar and a small area of paresthesia persisted even after 5 years.

摘要

我们在此呈现一例在计划进行牙髓治疗的患者中，意外注射次氯酸钠而非局部麻醉剂后出现组织破坏和感觉异常的病例。该意外通过局部注射类固醇、清创坏死组织、每日换药及用药进行处理。1个月末伤口愈合情况良好。即使在5年后，仍遗留一处口外瘢痕和一小片感觉异常区域。

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本文引用的文献

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Effect of submucosal injection of dexamethasone on postoperative discomfort after third molar surgery: a prospective study.黏膜下注射地塞米松对第三磨牙手术后不适的影响：一项前瞻性研究。
J Oral Maxillofac Surg. 2007 Nov;65(11):2218-26. doi: 10.1016/j.joms.2006.11.036.
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Neurological complications following extrusion of sodium hypochlorite solution during root canal treatment.根管治疗期间次氯酸钠溶液渗出后的神经并发症
Int Endod J. 2005 Nov;38(11):843-8. doi: 10.1111/j.1365-2591.2005.01017.x.
3
Severe tissue damage and neurological deficit following extravasation of sodium hypochlorite solution during routine endodontic treatment.常规根管治疗期间次氯酸钠溶液外渗后出现严重组织损伤和神经功能缺损。
Br Dent J. 2005 Jun 25;198(12):749-50. doi: 10.1038/sj.bdj.4812414.
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Toxicity of concentrated sodium hypochlorite used as an endodontic irrigant.用作根管冲洗剂的浓次氯酸钠的毒性
Int Endod J. 2004 Apr;37(4):272-80. doi: 10.1111/j.0143-2885.2004.00804.x.
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Treatment protocol for the management of a sodium hypochlorite accident during endodontic therapy.根管治疗期间次氯酸钠事故处理方案
Gen Dent. 2001 May-Jun;49(3):278-81.
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Complications during root canal irrigation--literature review and case reports.根管冲洗过程中的并发症——文献综述与病例报告
Int Endod J. 2000 May;33(3):186-93. doi: 10.1046/j.1365-2591.2000.00303.x.
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Cytotoxic effects of NaOCl on vital tissue.次氯酸钠对活体组织的细胞毒性作用。
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Long-term paresthesia following inadvertent forcing of sodium hypochlorite through perforation in maxillary incisor.因不慎将次氯酸钠强行通过上颌切牙穿孔处注入而导致的长期感觉异常。
Endod Dent Traumatol. 1989 Aug;5(4):200-3. doi: 10.1111/j.1600-9657.1989.tb00361.x.
9
Effects of sodium hypochlorite on soft tissues after its inadvertent injection beyond the root apex.次氯酸钠意外注射至根尖外后对软组织的影响。
J Endod. 1991 Nov;17(11):573-4. doi: 10.1016/S0099-2399(06)81725-5.