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干细胞在牙齿生物工程中的作用。

Role of stem cells in tooth bioengineering.

作者信息

Singh Kamleshwar, Mishra Niraj, Kumar Lakshya, Agarwal Kaushal Kishore, Agarwal Bhaskar

机构信息

Assistant Professor, Department of Prosthodontics and Dental Material Sciences, Faculty of Dental Sciences, CSM Medical University, Lucknow, Uttar Pradesh, India.

Lecturer, Department of Prosthodontics and Dental Material Sciences, Faculty of Dental Sciences, CSM Medical University, Lucknow, Uttar Pradesh, India.

出版信息

J Oral Biol Craniofac Res. 2012 Jan-Apr;2(1):41-5. doi: 10.1016/S2212-4268(12)60010-4.

Abstract

The creation of teeth in the laboratory depends upon the manipulation of stem cells and requires a synergy of all cellular and molecular events that finally lead to the formation of tooth-specific hard tissues, dentin, and enamel. This review focuses on the different sources of stem cells that have been used for making teeth in vitro. The search was performed from 1970 to 2012 and was limited to English language papers. The keywords searched on medline were 'stem cells and dentistry,' 'stem cells and odontoblast,' 'stem cells and dentin,' and 'stem cells and ameloblasts.'

摘要

在实验室中制造牙齿依赖于干细胞的操控,并且需要所有细胞和分子事件协同作用,最终导致形成牙齿特有的硬组织——牙本质和釉质。本综述聚焦于已用于体外制造牙齿的不同干细胞来源。检索时间为1970年至2012年,且仅限于英文论文。在医学在线数据库(Medline)上搜索的关键词为“干细胞与牙科”、“干细胞与成牙本质细胞”、“干细胞与牙本质”以及“干细胞与成釉细胞”。

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