Coppola A
UOS Chest Pain Unit, Azienda Policlinico Umberto I Roma.
Clin Ter. 2015;166(1):26-31. doi: 10.7417/CT.2015.1798.
Myocardial ischemia is caused in most cases by the obstruction of epicardial coronary vessels. Several studies, however, have shown that abnormalities in the coronary microcirculation can also contribute to myocardial ischemia. Microvascular dysfuntion is defined as primary microvascular angina (MVA) to distinguish it from other forms of secondary microvascular angina due to such diseases as arterial hypertension, left ventricular hypertrophy, myocardial disease, metabolic syndrome and collagen diseases. We present the case report of a 48-year-old male patient who coronarographically showed coronary slow flow with delayed distal vessel opacification in the absence of coronary stenosis. Whilst this phenomenon is still not completely understood, strong evidence suggests that the primary alteration is caused by a dysfunction of small coronary vessels.
大多数情况下，心肌缺血是由心外膜冠状动脉血管阻塞引起的。然而，多项研究表明，冠状动脉微循环异常也可导致心肌缺血。微血管功能障碍被定义为原发性微血管性心绞痛（MVA），以区别于由动脉高血压、左心室肥厚、心肌疾病、代谢综合征和胶原疾病等引起的其他形式的继发性微血管性心绞痛。我们报告一例48岁男性患者的病例，该患者冠状动脉造影显示在无冠状动脉狭窄的情况下冠状动脉血流缓慢且远端血管显影延迟。虽然这种现象仍未完全明确，但有力证据表明主要病变是由小冠状动脉血管功能障碍引起的。
