恒河猴食用致动脉粥样化饮食后对肠道营养物质吸收及刷状缘膜酶的影响。
Effects on intestinal nutrient uptake and brush border membrane enzymes in response to atherogenic diet in rhesus monkeys.
作者信息
Dhaunsi G S, Sidhu G S, Garg U C, Singh Y, Chakravarti R N, Bhatnagar R
机构信息
Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
J Med Primatol. 1989;18(6):467-75.
Transport of nutrients and kinetic parameters (Vmax and Km) of brush border membrane (BBM) enzymes were studied in duodenum, jejunum, and ileum from atherogenic diet-fed monkeys. The Km remained unaltered while feeding of atherogenic diet resulted in higher Vmax of sucrase, maltase, and alkaline phosphatase and lower Vmax of gamma-glutamyltranspeptidase and leucine-aminopeptidase compared to controls. Na+-dependent D-glucose transport was higher in duodenum and jejunum and unaltered in ileum. In contrast to D-glucose transport, the transport of amino acids was decreased in all three intestinal segments from atherogenic diet-fed monkeys.
在喂食致动脉粥样硬化饮食的猴子的十二指肠、空肠和回肠中，研究了刷状缘膜（BBM）酶的营养物质转运和动力学参数（Vmax和Km）。与对照组相比，喂食致动脉粥样硬化饮食时，蔗糖酶、麦芽糖酶和碱性磷酸酶的Km保持不变，而Vmax升高；γ-谷氨酰转肽酶和亮氨酸氨肽酶的Vmax降低。钠依赖性D-葡萄糖转运在十二指肠和空肠中较高，在回肠中不变。与D-葡萄糖转运相反，喂食致动脉粥样硬化饮食的猴子的所有三个肠段中氨基酸转运均减少。
Zotero 插件