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棕榈酸哌泊噻嗪与癸酸氟奋乃静维持精神分裂症缓解的对比研究

A comparative study of pipothiazine palmitate and fluphenazine decanoate in the maintenance of remission of schizophrenia.

作者信息

Leong O K, Wong K E, Tay W K, Gill R C

出版信息

Singapore Med J. 1989 Oct;30(5):436-40.

PMID:2575796
Abstract

This paper reports a randomized, controlled, partially-blinded, flexible dose, parallel group, comparative study of the efficacy and tolerance of pipothiazine palmitate and fluphenazine decanoate in patients in remission from Schizophrenia over a 28 week period. The results show that pipothiazine palmitate is at least as efficacious and well-tolerated as fluphenazine decanoate in preventing relapses from maintained Schizophrenia.

摘要

本文报告了一项随机、对照、部分盲法、灵活剂量、平行组的比较研究,该研究针对精神分裂症缓解期患者,在28周期间比较了棕榈酸哌泊噻嗪和癸酸氟奋乃静的疗效及耐受性。结果显示,在预防持续型精神分裂症复发方面,棕榈酸哌泊噻嗪的疗效和耐受性至少与癸酸氟奋乃静相当。

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