Said Joseph I, Knapka Joseph A, Song Mingzhou, Zhang Jinfa
Department of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM, USA,
Mol Genet Genomics. 2015 Aug;290(4):1615-25. doi: 10.1007/s00438-015-1021-y. Epub 2015 Mar 11.
A specialized database currently containing more than 2200 QTL is established, which allows graphic presentation, visualization and submission of QTL. In cotton quantitative trait loci (QTL), studies are focused on intraspecific Gossypium hirsutum and interspecific G. hirsutum × G. barbadense populations. These two populations are commercially important for the textile industry and are evaluated for fiber quality, yield, seed quality, resistance, physiological, and morphological trait QTL. With meta-analysis data based on the vast amount of QTL studies in cotton it will be beneficial to organize the data into a functional database for the cotton community. Here we provide a tool for cotton researchers to visualize previously identified QTL and submit their own QTL to the Cotton QTLdb database. The database provides the user with the option of selecting various QTL trait types from either the G. hirsutum or G. hirsutum × G. barbadense populations. Based on the user's QTL trait selection, graphical representations of chromosomes of the population selected are displayed in publication ready images. The database also provides users with trait information on QTL, LOD scores, and explained phenotypic variances for all QTL selected. The CottonQTLdb database provides cotton geneticist and breeders with statistical data on cotton QTL previously identified and provides a visualization tool to view QTL positions on chromosomes. Currently the database (Release 1) contains 2274 QTLs, and succeeding QTL studies will be updated regularly by the curators and members of the cotton community that contribute their data to keep the database current. The database is accessible from http://www.cottonqtldb.org.
目前已建立了一个专门的数据库，其中包含2200多个数量性状基因座（QTL），该数据库支持QTL的图形展示、可视化及提交。在棉花数量性状基因座研究中，重点关注陆地棉种内群体以及陆地棉×海岛棉种间群体。这两个群体对纺织工业具有重要商业价值，并针对纤维品质、产量、种子质量、抗性、生理和形态性状QTL进行评估。基于棉花大量QTL研究的元分析数据，将这些数据整理成一个面向棉花领域的功能数据库将大有裨益。在此，我们为棉花研究人员提供了一个工具，用于可视化先前鉴定的QTL，并将他们自己的QTL提交至棉花QTL数据库（Cotton QTLdb）。该数据库为用户提供了从陆地棉或陆地棉×海岛棉群体中选择各种QTL性状类型的选项。根据用户选择的QTL性状，所选群体染色体的图形表示将以适合发表的图像形式展示。该数据库还为用户提供所选所有QTL的性状信息、LOD分数以及解释的表型变异。棉花QTL数据库（CottonQTLdb）为棉花遗传学家和育种者提供了先前鉴定的棉花QTL的统计数据，并提供了一个可视化工具来查看染色体上QTL的位置。目前该数据库（版本1）包含2274个QTL，后续的QTL研究将由管理员和贡献数据的棉花领域成员定期更新，以保持数据库的时效性。可通过http://www.cottonqtldb.org访问该数据库。
