Lajos Giuliane J, Tedesco Ricardo P, Passini Renato, Dias Tabata Z, Nomura Marcelo L, Rehder Patrícia M, Haddad Samira M, Sousa Maria H, Cecatti Jose G
Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, 13083-881 Campinas, SP, Brazil.
Center for Studies in Reproductive Health of Campinas (CEMICAMP), 13083-881 Campinas, SP, Brazil.
ScientificWorldJournal. 2015;2015:719104. doi: 10.1155/2015/719104. Epub 2015 Feb 10.
Assuming that the occurrence of preterm births and their maternal and neonatal associated conditions in Brazil are not completely known, a multicenter study was proposed. The purpose of this paper is to describe the methods used, its processes, achievements, and challenges.
A multicenter cross-sectional study on preterm births in Brazilian facilities plus a nested case-control study to assess their associated factors. A description of all steps of planning and implementing such a nationwide study, including strategies for dealing with problems arising during the process, is presented.
20 referral hospitals in different regions of Brazil participated in the study. A detailed questionnaire for data collection, an electronic platform for data transcription and monitoring, research materials, and specific monitoring tools were developed; then data management and analyses were performed. Finally, we got information on 4,150 preterm births and 1,146 term births.
This study represented the first step of a planned comprehensive assessment of preterm birth in Brazil, with detailed information that will lead to several analyses and further studies, bringing the knowledge to improve screening, diagnosis, and treatment practices in maternal and perinatal health with the final purpose of reducing the burden of this condition in the country.
鉴于巴西早产及其母婴相关情况的发生率尚不完全清楚，故开展了一项多中心研究。本文旨在描述所采用的方法、其过程、成果及挑战。
对巴西医疗机构中的早产情况进行多中心横断面研究，并开展一项巢式病例对照研究以评估相关因素。本文介绍了在全国范围内开展此类研究的规划与实施的所有步骤，包括应对过程中出现问题的策略。
巴西不同地区的20家转诊医院参与了该研究。开发了用于数据收集的详细问卷、用于数据转录和监测的电子平台、研究材料及特定监测工具；随后进行了数据管理与分析。最终，我们获得了4150例早产和1146例足月产的信息。
本研究是巴西对早产进行计划性全面评估的第一步，所获详细信息将促成多项分析及进一步研究，为改善孕产妇和围产期健康的筛查、诊断及治疗实践提供知识，最终目的是减轻该国这一病症的负担。
