Universidade Estadual de Campinas, Campinas, SP, Brazil.
Faculdade de Medicina de Jundiaí, Jundiaí, SP, Brazil.
Einstein (Sao Paulo). 2024 May 20;22:eAO0514. doi: 10.31744/einstein_journal/2024AO0514. eCollection 2024.
This study aimed to evaluate the prevalence of hypertensive disorders during pregnancy among Brazilian women with preterm births and to compare the epidemiological characteristics and perinatal outcomes among preterm births of women with and without hypertension.
This was a secondary cross-sectional analysis of the Brazilian Multicenter Study on Preterm Birth. During the study period, all women with preterm births were included and further split into two groups according to the occurrence of any hypertensive disorder during pregnancy. Prevalence ratios were calculated for each variable. Maternal characteristics, prenatal care, and gestational and perinatal outcomes were compared between the two groups using χ2 and t-tests.
A total of 4,150 women with preterm births were included, and 1,169 (28.2%) were identified as having hypertensive disorders. Advanced maternal age (prevalence ratio (PR) 2.49) and obesity (PR= 2.64) were more common in the hypertensive group. The gestational outcomes were worse in women with hypertension. Early preterm births were also more frequent in women with hypertension.
Hypertensive disorders of pregnancy were frequent among women with preterm births, and provider-initiated preterm births were the leading causes of premature births in this group. The factors significantly associated with hypertensive disorders among women with preterm births were obesity, excessive weight gain, and higher maternal age.
本研究旨在评估巴西早产妇女妊娠高血压疾病的患病率，并比较高血压与非高血压孕妇早产的流行病学特征和围产结局。
这是巴西多中心早产研究的二次横断面分析。在研究期间，所有早产妇女均被纳入研究，并根据是否发生任何妊娠高血压疾病进一步分为两组。计算了每个变量的患病率比。采用 χ2 检验和 t 检验比较两组间的母亲特征、产前保健、妊娠和围产结局。
共纳入 4150 例早产妇女，其中 1169 例（28.2%）被诊断为患有妊娠高血压疾病。高血压组中，高龄产妇（患病率比（PR）2.49）和肥胖（PR=2.64）更为常见。高血压组的妊娠结局更差。高血压组的早期早产也更为常见。
妊娠高血压疾病在早产妇女中较为常见，且由医生决定的早产是该组早产的主要原因。与早产妇女妊娠高血压疾病显著相关的因素是肥胖、体重过度增加和较高的母亲年龄。
