Yoshida Rika, Kaji Yasushi, Tamaki Yukihisa, Katsube Takashi, Kitagaki Hajime, Kanbara Tsunehito, Kamai Takao
Department of Radiology, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, 693-8501, Japan,
Jpn J Radiol. 2015 May;33(5):246-52. doi: 10.1007/s11604-015-0407-4. Epub 2015 Mar 12.
We assessed which information from a prostate biopsy had the strongest relationship with prostate cancer detection by 3T-MRI.
Sixty-one consecutive patients with biopsy-proven prostate cancer who underwent 3T-MRI before biopsy were enrolled in this retrospective study. Two radiologists independently reviewed T2-weighted and diffusion-weighted images. When the cancer lesions were revealed by biopsy and MRI depicted them at corresponding sites, we classified these lesions as MRI-detectable cancer. If the cancer lesions were revealed by biopsy, but any cancers had not been detected, we classified these lesions as MRI-undetectable cancer. We compared the Gleason score (GS), cancer ratio (CaR) and cancer length (CaL) from core biopsies between the two groups.
GS, CaR and CaL differed significantly between the MRI-detectable group (N = 70), and the MRI-undetectable group (N = 73). 3T-MRI could detect cancer cores with a sensitivity of 90.5% in cores with CaR ≥ 60%, and with a sensitivity of 81.8% in those with CaL ≥ 5 mm. Receiver operating characteristic analysis showed that CaR (P = 0.006) and CaL (P = 0.010) significantly associated with the prostate cancer detection using MRI rather than GS.
CaR and CaL from the core biopsies showed a stronger relationship to detection of the prostate cancer on 3T-MRI than the GS did.
我们评估了前列腺活检中的哪些信息与3T磁共振成像（3T-MRI）检测前列腺癌的相关性最强。
本回顾性研究纳入了61例经活检证实为前列腺癌且在活检前接受了3T-MRI检查的连续患者。两名放射科医生独立审查T2加权图像和扩散加权图像。当活检发现癌症病灶且MRI在相应部位显示这些病灶时，我们将这些病灶分类为MRI可检测到的癌症。如果活检发现了癌症病灶，但MRI未检测到任何癌症，则将这些病灶分类为MRI不可检测到的癌症。我们比较了两组核心活检的Gleason评分（GS）、癌症比例（CaR）和癌症长度（CaL）。
MRI可检测组（N = 70）和MRI不可检测组（N = 73）之间的GS、CaR和CaL存在显著差异。3T-MRI对CaR≥60%的核心中癌症核心的检测灵敏度为90.5%，对CaL≥5 mm的核心中癌症核心的检测灵敏度为81.8%。受试者操作特征分析表明，与GS相比，CaR（P = 0.006）和CaL（P = 0.010）与使用MRI检测前列腺癌显著相关。
核心活检中的CaR和CaL与3T-MRI检测前列腺癌的相关性比GS更强。
